ADORA3

  • Official Full Name

    adenosine A3 receptor

  • Overview

    This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene.

  • Synonyms

    ADORA3;adenosine A3 receptor;adenosine receptor A3;AD026;A3AR;A3R;AA3R;AA3R_HUMAN;AD 026;ADORA 3;ARA3;bA552M11.5;Gpcr2;RP11 552M11.7;TGPCR1;RP11-552M11.7

Recombinant Proteins

  • Rhesus macaque
  • Rat
  • Human
  • Chicken
  • Oryctolagus cuniculus (Rabbit)
  • Sheep
  • Bovine
  • Dog
  • Mus musculus
  • Mammalian Cell
  • E.Coli or Yeast
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • E.coli expression system
  • His
  • Non
  • GST
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
ADORA3-255R Recombinant Rhesus monkey ADORA3 Protein, His-tagged Mammalian Cell Rhesus macaque His
Adora3-3165R Recombinant Rat Adora3, His-tagged E.Coli or Yeast Rat His 320
ADORA3-371H Recombinant Human ADORA3 Protein Wheat Germ Human Non
ADORA3-372H Recombinant Human ADORA3 Protein, GST-tagged Wheat Germ Human GST
ADORA3-535R Recombinant Rat ADORA3 Protein Mammalian Cell Rat His
ADORA3-5727C Recombinant Chicken ADORA3 Mammalian Cell Chicken His
ADORA3-12HCL Recombinant Human ADORA3 lysate HEK293 Human Non
ADORA3-191R Recombinant Rat ADORA3 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
ADORA3-191R-B Recombinant Rat ADORA3 Protein Pre-coupled Magnetic Beads HEK293 Rat
ADORA3-26898TH Recombinant Human ADORA3 Wheat Germ Human Non 105 amino acids
ADORA3-83R Recombinant Rhesus Macaque ADORA3 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
ADORA3-83R-B Recombinant Rhesus Macaque ADORA3 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
ADORA3-968HF Recombinant Full Length Human ADORA3 Protein In Vitro Cell Free System Human Full L. 318 amino acids
RFL-13297RF Recombinant Full Length Rat Adenosine Receptor A3(Adora3) Protein, His-Tagged E.coli expression system Rat His Full L. Full Length (1-320)
RFL-15125OF Recombinant Full Length Rabbit Adenosine Receptor A3(Adora3) Protein, His-Tagged E.coli expression system Oryctolagus cuniculus (Rabbit) His Full L. Full Length (1-319)
RFL-17161OF Recombinant Full Length Sheep Adenosine Receptor A3(Adora3) Protein, His-Tagged E.coli expression system Sheep His Full L. Full Length (1-317)
RFL19118BF Recombinant Full Length Bovine Adenosine Receptor A3(Adora3) Protein, His-Tagged E.coli expression system Bovine His Full L. Full Length (1-317)
RFL21718CF Recombinant Full Length Dog Adenosine Receptor A3(Adora3) Protein, His-Tagged E.coli expression system Dog His Full L. Full Length (1-314)
RFL32181MF Recombinant Full Length Mouse Adenosine Receptor A3(Adora3) Protein, His-Tagged E.coli expression system Mus musculus His Full L. Full Length (1-319)

    Involved Pathway

    ADORA3 involved in several pathways and played different roles in them. We selected most pathways ADORA3 participated on our site, such as Adenosine P1 receptors,Class A/1 (Rhodopsin-like receptors),G alpha (i) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADORA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    GPCR ligand binding FPR-RS6,PTHRP2,CALCRL,AGT,GPR37L1,NTS,OXGR1A.3,PTGDR2,RAMP3,CCL27
    GPCR downstream signaling NMUR1,LPAR1,HEBP1,DGKQ,TAC2,QRFPR,GPR4,SCT,GPR55A,ADM2
    GPCRs, Class A Rhodopsin-like OR3A4P,GPR37L1,GPR3,FPR-RS3,PTGDR2,OR10A5,CNR1,GPR65,GPR18,SSTR5
    GPCRs, Other RRH,OR3A4P,CELSR2,EMR3,CELSR3,GPR88,VMN1R47,LGR6,CELSR1,VMN1R50
    Class A/1 (Rhodopsin-like receptors) OPN1LW2,GPR17,OPN1SW1,OXGR1A.1,GPR65,SAA1,SSTR3,GPR55,OPN1SW,GPR120
    G alpha (i) signalling events GAL,SST1.1,RGS18,OXER1,LPAR5A,RGS1,TAS2R13,PENKB,NMUR1,RGS14
    Adenosine P1 receptors ADORA2A,ADORA1,ADORA2B
    Neuroactive ligand-receptor interaction GRIN3B,GRM3,NPY5R,GRIK4,RXFP4,HTR1D,S1PR5,GABRA6,GABRA4,HRH1

    Protein Function

    ADORA3 has several biochemical functions, for example, G-protein coupled adenosine receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADORA3 itself. We selected most functions ADORA3 had, and list some proteins which have the same functions with ADORA3. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled adenosine receptor activity ADORA2AB,ADORA1,ADORA2B,ADORA2AA,ADORA2A,P2RY12

    Interacting Protein

    ADORA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADORA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADORA3.

    ab-meca;ib-meca

    Resources

    Gene Families

    What is GPCR

    Research Area

    Inflammatory Bowel Diseases Therapeutic Targets
    Reperfusion Injury Therapeutic Targets

    References

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