ADORA2B
-
Official Full Name
adenosine A2b receptor -
Overview
This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17. -
Synonyms
ADORA2B;adenosine A2b receptor;adenosine receptor A2b;ADORA2
Recombinant Proteins
- Human
- Mouse
- Rat
- Chicken
- Zebrafish
- Bovine
- Oryctolagus cuniculus (Rabbit)
- Mus musculus
- Dog
- E.coli
- Mammalian Cells
- E.Coli/Yeast
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- SUMO
- Non
- Avi
- Fc
Involved Pathway
ADORA2B involved in several pathways and played different roles in them. We selected most pathways ADORA2B participated on our site, such as Adenosine P1 receptors,Alcoholism,C-MYB transcription factor network, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADORA2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Calcium signaling pathway | PDE1A,CHRM5B,PLCG2,ADORA2AB,CACNA1G,PLCD1B,PRKCG,P2RX3,TRHRB,PTGER3 |
| C-MYB transcription factor network | CDK6,YEATS4,MYF6,CREBBP,CSF1R,PPID,PTCRA,SMARCA2,CEBPA,MYC |
| GPCR ligand binding | TAC1,PRLH,GRP,TAS2R16,FPR-RS3,DRD3,CRHR2,CXCR7B,CCL35.2,OXGR1A.2 |
| GPCR downstream signaling | TAC2,ARHGEF1B,PMCH,CXCL11.8,OR56A1,OBSCN,DRD2,NPSR1,GPRC6A,NPB |
| Alcoholism | PDYN,HIST1H2BE,HIST1H2BI,GNGT2,HIST1H2BG,HIST4H4,CALML5,SHC4,GRIN3B,CAMKK1 |
| Class A/1 (Rhodopsin-like receptors) | CCK,CHRM5,GPBAR1,NPFF,EDN3,PENKA,NMU,PROKR1,SSTR1,PROKR1A |
| G alpha (s) signalling events | SCT,CRHB,ADCYAP1B,CALCA,RAMP1,NPSR1,DRD5,CALCB,PDE10A,RXFP2B |
| Adenosine P1 receptors | ADORA3,ADORA2A,ADORA1 |
Protein Function
ADORA2B has several biochemical functions, for example, G-protein coupled adenosine receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADORA2B itself. We selected most functions ADORA2B had, and list some proteins which have the same functions with ADORA2B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein coupled adenosine receptor activity | P2RY12,ADORA2A,ADORA1,ADORA2AA,ADORA2AB,ADORA3 |
Interacting Protein
ADORA2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADORA2B here. Most of them are supplied by our site. Hope this information will be useful for your research of ADORA2B.
TPD52L2;ZNF267
Resources
Related Services
Related Products
References
