ACTR3
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Official Full Name
ARP3 actin-related protein 3 homolog (yeast) -
Overview
Actin nucleation, the formation of new actin filaments from existing filaments, affects actin filament structure during cell motility, division, and intracellular trafficking. An important actin nucleation protein complex is the highly conserved ARP2/3 co -
Synonyms
ACTR3;ARP3 actin-related protein 3 homolog (yeast);ARP3 (actin related protein 3, yeast) homolog;actin-related protein 3;ARP3;actin-like protein 3
Recombinant Proteins
- Zebrafish
- Human
- Bovine
- Rat
- Chicken
- Mouse
- Mammalian Cell
- Wheat Germ
- E.Coli or Yeast
- E.coli
- Insect Cell
- HEK293
- Mammalian cells
- HEK293T
- Human Cells
- In Vitro Cell Free System
- His
- GST
- His&GST
- Non
- Flag
- His&Fc&Avi
- Myc&DDK
- His&Myc
Involved Pathway
ACTR3 involved in several pathways and played different roles in them. We selected most pathways ACTR3 participated on our site, such as Axon guidance,B Cell Receptor Signaling Pathway,CDC42 signaling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACTR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Developmental Biology | LGI1A,FRS2B,NR5A1,HIF3A,RASGRP1,RHOB,SCN3A,SMAD3B,STX1B,CEBPB |
| ErbB1 downstream signaling | EGR1,ABI1,ARF4,NCKAP1,EPS8,BAIAP2,MAP3K2,CHN2,ACTR2,WASF2 |
| CDC42 signaling events | ARPC4,TNK2,BAIAP2,CFL1,PAK4,ARPC1B,IQGAP3,CDC42BPA,CTNNA1,ARPC5 |
| EPH-Ephrin signaling | ARPC2,EFNA4,CLTB,MYL12B,AP2B1,EFNB3B,KDR,EPHB4A,EPHB4B,EFNB3 |
| EPHB-mediated forward signaling | EFNB2,EFNB3,EPHB3A,ARPC1A,EPHB4B,ARHGEF28,CFL1,ARPC2,ITSN1,ACTR2B |
| Fcgamma receptor (FCGR) dependent phagocytosis | PPAPDC1B,ABI1B,MYO9B,WASF3,WIPF2,IgG3,NCKIPSD,PPAPDC1A,NCKAP1,DOCK1 |
| Axon guidance | RNF8,EFNB2,EPHA3,JAK2,Ntng2,EPHB4,DPYSL5B,SRGAP2,SCN3A,EPHA7 |
| B Cell Receptor Signaling Pathway | GRB2,CTNNB2,TTC6,BTK,NFKB1,RAP2A,NRAS,MAP2K2,FOS,RASGRP3 |
Protein Function
ACTR3 has several biochemical functions, for example, ATP binding,contributes_to actin filament binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACTR3 itself. We selected most functions ACTR3 had, and list some proteins which have the same functions with ACTR3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| contributes_to actin filament binding | ARPC2,MYH10,ACTR2,ARPC4,ARPC3,ARPC5,ARPC1B,MYH9 |
| ATP binding | CSNK1DB,NEK8,ATP2B4,PRKAG1,C9orf96,TNIKA,ABCC2,CTPS2,AK4,SUCLA2 |
| structural constituent of cytoskeleton | TUBA8L2,ACTB,TUBB6,TUBGCP3,TUBA4A,TLN1,TUBA1L,CCDC6,BKJ,TUBGCP5 |
| protein binding | VSNL1,MTDH,DTX3L,EXOC3,RIOK3,IFRD2,NIPAL3,GAPDH,TRMT112,RBMX2 |
Interacting Protein
ACTR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACTR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACTR3.
JUND;EIF1B;Cdk1;TRAF6;pepP;q81ng4_bacan;q81r97_bacan;FN1;ESR1;CAT;Itga5;CD44;VCAM1;FLNA;MYH9;MYH11
ACTR3 Related Signal Pathway
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References
- Uhrig, JF; Mutondo, M; et al. The role of Arabidopsis SCAR genes in ARP2-ARP3-dependent cell morphogenesis. DEVELOPMENT 134:967-977(2007).
- Hudson, AM; Cooley, L; et al. A subset of dynamic actin rearrangements in Drosophila requires the Arp2/3 complex. JOURNAL OF CELL BIOLOGY 156:677-687(2002).
