ACTR1B
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Official Full Name
ARP1 actin-related protein 1 homolog B, centractin beta (yeast) -
Overview
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size;from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of;cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle;formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related;protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant;ratio of approximately 1:15 in the dynactin complex. -
Synonyms
ACTR1B;ARP1 actin-related protein 1 homolog B, centractin beta (yeast);ARP1 (actin related protein 1, yeast) homolog B (centractin beta) , CTRN2;beta-centractin;Actin related protein 1B;Actin-related protein 1B;ACTR 1B;ACTY_HUMAN;ARP 1B;ARP1 actin related protein 1 homolog B;ARP1 actin related protein 1 homolog B centractin beta (yeast);ARP1 actin related protein 1 homolog B centractin beta;ARP1 actin related protein 1 yeast homolog B centractin beta;ARP1 yeast homolog B;ARP1B;Beta centractin;Centractin beta (Yeast);Centractin beta;CTRN 2;CTRN2;PC 3;PC3
Recombinant Proteins
- Mouse
- Rhesus macaque
- Human
- Mammalian Cell
- Wheat Germ
- E.coli
- HEK293
- HEK293T
- Human Cells
- In Vitro Cell Free System
- His
- GST
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
ACTR1B involved in several pathways and played different roles in them. We selected most pathways ACTR1B participated on our site, such as Adaptive Immune System,Immune System,MHC class II antigen presentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACTR1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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MHC class II antigen presentation | KIF15,KLC3,CTSH,DYNC1LI2,MGC174152,KIF26A,IFI30,DYNC1I1,KIFAP3,RACGAP1 |
Adaptive Immune System | KLHL20,RNF123,AP2A2,HBEGF,DYNC1LI2,RNF220,AGO2,AKT3,CD300LD,CXADR |
Immune System | SRMS,CLEC2H,CD200,ACTR2B,TREM1,GRAP2A,LTN1,ASB3,OSCAR,TAX1BP1B |
Protein Function
ACTR1B has several biochemical functions, for example, ATP binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACTR1B itself. We selected most functions ACTR1B had, and list some proteins which have the same functions with ACTR1B. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
protein binding | C7orf49,SIL1,HPN,MYH9,HBB,NOTCH4,CD33,RG9MTD1,SERPINE1,SLC25A5 |
ATP binding | MAP2K3,ROCK2A,DYNC1LI2,NLRP1,UBE2Q1,MAPK13,YARS2,ROS1,QARS,KIF14 |
Interacting Protein
ACTR1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACTR1B here. Most of them are supplied by our site. Hope this information will be useful for your research of ACTR1B.
Dctn1;Dctn2;Dctn3;Capza1;ACTB;Actr1a;DCTN1;Actr10;TK1;CSNK2B;CHD3;MAPK6;ZDHHC17;LRRK2;Dctn4
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