ACOT11
-
Official Full Name
acyl-CoA thioesterase 11 -
Overview
This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. -
Synonyms
ACOT11;acyl-CoA thioesterase 11;THEA, thioesterase, adipose associated;acyl-coenzyme A thioesterase 11;BFIT;BFIT1;KIAA0707;StAR related lipid transfer (START) domain containing 14;STARD14;THEM1;START domain containing 14;acyl-CoA thioester hyd
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ACOT11-9296H | Recombinant Human ACOT11, GST-tagged | E.coli | Human | GST | 1-221a.a. | |
| ACOT11-167H | Recombinant Human ACOT11 Protein, GST-Tagged | Wheat Germ | Human | GST |
|
|
| BFIT-2436H | Recombinant human BFIT, His-tagged | E.coli | Human | His |
|
|
| ACOT11-6HCL | Recombinant Human ACOT11 lysate | HEK293 | Human | Non |
|
|
| ACOT11-784HF | Recombinant Full Length Human ACOT11 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 594 amino acids |
|
Involved Pathway
ACOT11 involved in several pathways and played different roles in them. We selected most pathways ACOT11 participated on our site, such as Fatty Acyl-CoA Biosynthesis,Fatty acid, triacylglycerol, and ketone body metabolism,Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACOT11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Triglyceride Biosynthesis | SLC25A1A,ACOT11A,ACSF2,ACOT12,ACOT9.1,SLC25A1,Agmo,THEM5,ACOT6,ACOT9.2 |
| Metabolism of lipids and lipoproteins | MTF1,CDK19,SCP2B,SIN3B,ACOT9.2,FAM213B,CEPT1A,ARSK,PITPNB,FABP9 |
| Metabolism | GLTPD1,SYT5,SCO1,ARSH,MED26,ST3GAL3A,CDS1,Sult2a2,ITPKB,DBH |
| Fatty Acyl-CoA Biosynthesis | ACOT9.1,ACOT13,SLC25A1A,THEM5,ACOT2,ACOT11B,ACOT8,ACOT9.2,ACOT12,ELOVL1A |
| Fatty acid, triacylglycerol, and ketone body metabolism | ACAD11,MED10,CDK19,CPT1B,MED7,AGPAT1,DECR1,ACSF2,MED31,PPARGC1B |
Protein Function
ACOT11 has several biochemical functions, for example, acyl-CoA hydrolase activity,carboxylic ester hydrolase activity,lipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACOT11 itself. We selected most functions ACOT11 had, and list some proteins which have the same functions with ACOT11. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| lipid binding | OSBPL9,PITPNM3,FAM123C,FABP10A,UNC119,S100A13,DOK7,PTGS1,CYTH2,DNM1L |
| carboxylic ester hydrolase activity | NCEH1A,FAM135A,BAAT,CES2,ACOT9,ACOT7,ACOT6,ACOT2,Ces2c,ABHD4 |
| acyl-CoA hydrolase activity | ACOT8,ACSBG2,ACOT10,ACOT1,ACOT5,ACOT2 |
Interacting Protein
ACOT11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACOT11 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACOT11.
pi3p;2_aha_camp
Resources
Related Services
Related Products
References
- Liu, XP; Yu, HY; et al. Biosynthesis of butenoic acid through fatty acid biosynthesis pathway in Escherichia coli. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 99:1795-1804(2015).
- Bi, HK; Yu, YH; et al. Xanthomonas campestris RpfB is a fatty Acyl-CoA ligase required to counteract the thioesterase activity of the RpfF diffusible signal factor (DSF) synthase. MOLECULAR MICROBIOLOGY 93:262-275(2014).
