ABHD1
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Official Full Name
abhydrolase domain containing 1 -
Overview
This gene is a member of the AB hydrolase superfamily and encodes a protein with an alpha/beta hydrolase fold. This domain is common to a number of hydrolytic enzymes of widely differing phylogenetic origins and catalytic functions. -
Synonyms
ABHD1;abhydrolase domain containing 1;abhydrolase domain-containing protein 1;FLJ36128;LABH1;ABHD1_HUMAN;Alpha/beta hydrolase domain containing protein 1;Lung alpha/beta hydrolase 1;Lung alpha/beta hydrolase protein 1
Recombinant Proteins
- Human
- Mouse
- Rat
- Mus musculus
- Bovine
- E. coli
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- E.coli expression system
- N-His
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
ABHD1 involved in several pathways and played different roles in them. We selected most pathways ABHD1 participated on our site, such as Assembly of collagen fibrils and other multimeric structures,Collagen formation,Crosslinking of collagen fibrils, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABHD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Extracellular matrix organization | COL10A1A,MFAP3,LTBP2,COL1A1,ADAMTS18,COL28A1D,CMA1,MMP12,MMP10,CAPNS1 |
| Crosslinking of collagen fibrils | TLL2,BMP1,BMP1A,LOXL1,TLL1,LOX,LOXL2,BMP1B,LOXL3,LOXL4 |
| Elastic fibre formation | FBLN1,MFAP2,ITGB3A,FURINB,EFEMP1,LOXL3,MFAP5,MFAP3,EFEMP2,LOXL1 |
| Collagen formation | COL8A1,CTSS,LEPRE1,PCOLCE,PCOLCE2,COL3A1,TLL1,COL6A2,COL8A1A,LEPREL1 |
| Assembly of collagen fibrils and other multimeric structures | LOXL2,PCOLCE,COL4A4,COL4A6,LOXL4,COL6A3,COL1A2,COL10A1A,COL1A1,COL3A1 |
Protein Function
ABHD1 has several biochemical functions, for example, copper ion binding,protein binding,protein-lysine 6-oxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ABHD1 itself. We selected most functions ABHD1 had, and list some proteins which have the same functions with ABHD1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein-lysine 6-oxidase activity | LOX,LOXL2A,LOXL4,LOXL3,POLR1B,LOXL2B,LOXL2 |
| scavenger receptor activity | HHIPL1,LOXL2B,VTNA,ENPP1,LOXL3B,LOXL3A,SCART1,POLR1B,SCARF2,COLEC12 |
| protein binding | SH3PXD2B,ADAM22,ZMAT4,USHBP1,LEPROT,ASF1A,NXT1,S100A14,TXNRD3,PRICKLE1 |
| copper ion binding | DBH,HEPHL1A,LOXL2,LOXL3,ATP7B,ANG,LOXL3B,HAMP,RNF7,CCS |
Interacting Protein
ABHD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABHD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABHD1.
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References
- Wiedl, T; Arni, S; et al. Activity-based proteomics: Identification of ABHD11 and ESD activities as potential biomarkers for human lung adenocarcinoma. JOURNAL OF PROTEOMICS 74:1884-1894(2011).
- Gabert, BJ; Kultz, D; et al. Osmoprotective proteome adjustments in mouse kidney papilla. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS 1814:435-448(2011).
