ABCB10
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Official Full Name
ATP-binding cassette, sub-family B (MDR/TAP), member 10 -
Overview
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra- and intra-cellular membranes.ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).This protein is a member of the MDR/TAP subfamily.Members of the MDR/TAP subfamily are involved in multidrug resistance.The function of this mitochondrial protein is unknown. -
Synonyms
ABCB10;ATP-binding cassette, sub-family B (MDR/TAP), member 10;ATP-binding cassette sub-family B member 10, mitochondrial;ABC transporter 10 protein;ATP binding cassette sub family B member 10;mitochondrial;ATP binding cassette transporter 10;EST20237;M ABC2;mitochondrial ATP binding cassette 2;MTABC2;ABCB10 ATP binding cassette, sub family B (MDR/TAP), member 10;ABCBA_HUMAN;ATP binding cassette sub family B member 10, mitochondrial;ATP-binding cassette sub-family B member 10;ATP-binding cassette transporter 10;M-ABC2;Mitochondrial ATP-binding cassette 2
Recombinant Proteins
- Human
- Mouse
- Mus musculus
- E.coli
- Wheat Germ
- Mammalian Cell
- Mammalian cell
- HEK293
- E.coli expression system
- His
- GST
- His&T7
- His&Flag
- His&Fc&Avi
Involved Pathway
ABCB10 involved in several pathways and played different roles in them. We selected most pathways ABCB10 participated on our site, such as ABC transporters, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCB10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| ABC transporters | ABCC4,ABCB1,ABCB1A,ABCC2,ABCG3,ABCA9,ABCB9,ABCC5,ABCG8,ABCA1B |
Protein Function
ABCB10 has several biochemical functions, for example, ATP binding,ATPase activity, coupled to transmembrane movement of substances,protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCB10 itself. We selected most functions ABCB10 had, and list some proteins which have the same functions with ABCB10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATPase activity, coupled to transmembrane movement of substances | ABCB5,ABCA9,ABCD3B,ABCA8,ABCB3L1,ABCC5,ABCD3,ABCA4A,DPY19L2,ABCG2A |
| ATP binding | CAD,ACTC1,KIF23,PIK3R4,RAD51L3,BMPR1BB,MTHFD1B,KARS,ABCD4,DDX17 |
| transporter activity | SLC26A3,TCOF1,NUP155,OSTA,SLC4A2A,ATP6AP1,SLC25A38A,SLC22A23,SLC2A15A,AP3S1 |
| protein homodimerization activity | SRF,IKZF3,HMGCS1,GRPEL2,IRAK1,VPS24,TFAP4,FGFR1OP,KCNK3,GSTA4 |
Interacting Protein
ABCB10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCB10 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCB10.
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References
- Kang, YK; et al. Expression of Multidrug Resistance Protein 1 in Human Hepatocellular Carcinoma. KOREAN JOURNAL OF PATHOLOGY 45:281-289(2011).
- Wong, LJC; Dimmock, D; et al. Utility of oligonucleotide array-based comparative genomic hybridization for detection of target gene deletions. CLINICAL CHEMISTRY 54:1141-1148(2008).
