AASDHPPT

  • Official Full Name

    aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
  • Overview

    The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.
  • Synonyms

    AASDHPPT;aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase;L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase;AASD PPT;CGI 80;LYS5;4 phosphopantetheinyl transferase;4-phosphopantetheinyl transferase;AASD-PPT;ADPPT_HUMAN;Alpha aminoadipic semialdehyde dehydrogenase phosphopantetheinyl transferase;Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase;HAH P;LYS2;LYS5 ortholog;CGI-80

Recombinant Proteins

  • Human
  • Mouse
  • Rhesus macaque
  • Zebrafish
  • Rat
  • Chicken
  • Wheat Germ
  • Mammalian Cell
  • E.coli
  • HEK293T
  • HEK293
  • In Vitro Cell Free System
  • GST
  • His
  • Non
  • Myc&DDK
  • His&Fc&Avi
  • His&SUMO
Cat.# Product name Source (Host) Species Tag Protein Length Price
AASDHPPT-025H Recombinant Human AASDHPPT Protein, GST-tagged Wheat Germ Human GST
AASDHPPT-1067M Recombinant Mouse AASDHPPT Protein Mammalian Cell Mouse His
AASDHPPT-175R Recombinant Rhesus monkey AASDHPPT Protein, His-tagged Mammalian Cell Rhesus macaque His
AASDHPPT-3410Z Recombinant Zebrafish AASDHPPT Mammalian Cell Zebrafish His
AASDHPPT-389R Recombinant Rat AASDHPPT Protein Mammalian Cell Rat His
AASDHPPT-5354C Recombinant Chicken AASDHPPT Mammalian Cell Chicken His
AASDHPPT-797H Recombinant Human AASDHPPT, His-tagged E.coli Human His
AASDHPPT-2HCL Recombinant Human AASDHPPT cell lysate Human Non
Aasdhppt-1458M Recombinant Mouse Aasdhppt Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
AASDHPPT-1479H Recombinant Human AASDHPPT Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
AASDHPPT-177M Recombinant Mouse AASDHPPT Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
AASDHPPT-177M-B Recombinant Mouse AASDHPPT Protein Pre-coupled Magnetic Beads HEK293 Mouse
AASDHPPT-44R Recombinant Rat AASDHPPT Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
AASDHPPT-44R-B Recombinant Rat AASDHPPT Protein Pre-coupled Magnetic Beads HEK293 Rat
AASDHPPT-4803H Recombinant Human AASDHPPT protein, His-SUMO-tagged E.coli Human His&SUMO 1-309aa
AASDHPPT-480H Recombinant Human AASDHPPT Protein, His-tagged E.coli Human His Met1~Ser309
AASDHPPT-4R Recombinant Rhesus Macaque AASDHPPT Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
AASDHPPT-4R-B Recombinant Rhesus Macaque AASDHPPT Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
AASDHPPT-760HF Recombinant Full Length Human AASDHPPT Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 309 amino acids

    Involved Pathway

    AASDHPPT involved in several pathways and played different roles in them. We selected most pathways AASDHPPT participated on our site, such as Pantothenate and CoA biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with AASDHPPT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Pantothenate and CoA biosynthesis DPYDB,PPCDC,PANK3,PANK4,VNN2,ENPP3,BCAT1,VNN1,PANK2,PPCS

    Protein Function

    AASDHPPT has several biochemical functions, for example, holo-[acyl-carrier-protein] synthase activity,magnesium ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AASDHPPT itself. We selected most functions AASDHPPT had, and list some proteins which have the same functions with AASDHPPT. You can find most of the proteins on our site.

    Function Related Protein
    protein binding Siglec1,RINL,ZNF502,SMARCA2,KIF20B,UBE2D4,GALNT3,CCK,SEPSECS,S100A7
    magnesium ion binding INPP1,RRAGC,SNRK,NT5C3L,ERN2,RPS6KA6,PDXK,PPM1BA,PKLR,WEE2

    Interacting Protein

    AASDHPPT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AASDHPPT here. Most of them are supplied by our site. Hope this information will be useful for your research of AASDHPPT.

    USP22;TRAF2;SIAH1;EIF1B;HLA-B;BABAM1;MDFI;SLX4;ULK2

    Resources

    References

    • Praphanphoj, V; Sacksteder, KA; et al. Identification of the alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase gene, the human ortholog of the yeast LYSS gene. MOLECULAR GENETICS AND METABOLISM 72:336-342(2001).

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