AASDHPPT
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Official Full Name
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase -
Overview
The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia. -
Synonyms
AASDHPPT;aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase;L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase;AASD PPT;CGI 80;LYS5;4 phosphopantetheinyl transferase;4-phosphopantetheinyl transferase;AASD-PPT;ADPPT_HUMAN;Alpha aminoadipic semialdehyde dehydrogenase phosphopantetheinyl transferase;Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase;HAH P;LYS2;LYS5 ortholog;CGI-80
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Zebrafish
- Rat
- Chicken
- Wheat Germ
- Mammalian Cell
- E.coli
- HEK293T
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
- His&SUMO
Involved Pathway
AASDHPPT involved in several pathways and played different roles in them. We selected most pathways AASDHPPT participated on our site, such as Pantothenate and CoA biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with AASDHPPT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Pantothenate and CoA biosynthesis | DPYDB,PPCDC,PANK3,PANK4,VNN2,ENPP3,BCAT1,VNN1,PANK2,PPCS |
Protein Function
AASDHPPT has several biochemical functions, for example, holo-[acyl-carrier-protein] synthase activity,magnesium ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AASDHPPT itself. We selected most functions AASDHPPT had, and list some proteins which have the same functions with AASDHPPT. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
protein binding | Siglec1,RINL,ZNF502,SMARCA2,KIF20B,UBE2D4,GALNT3,CCK,SEPSECS,S100A7 |
magnesium ion binding | INPP1,RRAGC,SNRK,NT5C3L,ERN2,RPS6KA6,PDXK,PPM1BA,PKLR,WEE2 |
Interacting Protein
AASDHPPT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AASDHPPT here. Most of them are supplied by our site. Hope this information will be useful for your research of AASDHPPT.
USP22;TRAF2;SIAH1;EIF1B;HLA-B;BABAM1;MDFI;SLX4;ULK2
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References
- Praphanphoj, V; Sacksteder, KA; et al. Identification of the alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase gene, the human ortholog of the yeast LYSS gene. MOLECULAR GENETICS AND METABOLISM 72:336-342(2001).