ZSCAN4
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Official Full Name
zinc finger and SCAN domain containing 4 -
Overview
The ZSCAN4 gene encodes a protein involved in telomere maintenance and with a key role in the critical feature of mouse embryonic stem (ES) cells, namely, defying cellular senescence and maintaining normal karyotype for many cell divisions in culture (Zalzman et al., 2010 [PubMed 20336070]).[supplied by OMIM, May 2010] -
Synonyms
ZSCAN4;zinc finger and SCAN domain containing 4;ZNF494;zinc finger and SCAN domain-containing protein 4;zinc finger protein 494
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ZSCAN4-2636H | Recombinant Human ZSCAN4 protein, His-tagged | E.coli | Human | His | 98-302 aa | |
| ZSCAN4-196H | Recombinant Human ZSCAN4 protein, T7/His-tagged | E.coli | Human | His&T7 |
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| ZSCAN4-9184HCL | Recombinant Human ZSCAN4 293 Cell Lysate | HEK293 | Human | Non |
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Involved Pathway
ZSCAN4 involved in several pathways and played different roles in them. We selected most pathways ZSCAN4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ZSCAN4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
ZSCAN4 has several biochemical functions, for example, metal ion binding,sequence-specific DNA binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZSCAN4 itself. We selected most functions ZSCAN4 had, and list some proteins which have the same functions with ZSCAN4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, sequence-specific DNA binding | POU4F3,EOMES,NEUROG1,RUNX1T1,WT1A,NME2,L3MBTL4,STAT6,FOXI1,TCF7L1A |
| sequence-specific DNA binding | SNAI2,ATF6B,VRTN,SFPI1,SOX7,NKX3-1,EN2,CTCFL,FOXE3,GATAD2AB |
| metal ion binding | PDE5AB,DOHH,ZNF561,FGD5,ATP1A4,REPIN1,CYP2C39,CA5,SUMF2,ZNF330 |
Interacting Protein
ZSCAN4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZSCAN4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZSCAN4.
SMAD9;SMAD1
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References
- Lee, K; Gollahon, LS; et al. Zscan4 interacts directly with human Rap1 in cancer cells regardless of telomerase status. CANCER BIOLOGY & THERAPY 15:1094-1105(2014).
- Ko, SBH; Azuma, S; et al. Inflammation increases cells expressing ZSCAN4 and progenitor cell markers in the adult pancreas. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 304:G1103-G1116(2013).
