XPNPEP2
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Official Full Name
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound -
Overview
Aminopeptidase P is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. Structurally, the enzyme is a member of the pita bread fold family and occurs in mammalian tissues in both soluble and GPI-anchored membrane-bound forms.A membrane-bound and soluble form of this enzyme have been identified as products of two separate genes. -
Synonyms
XPNPEP2;X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound;xaa-Pro aminopeptidase 2;mAmP;membrane-bound APP;membrane-bound AmP;X-Pro aminopeptidase 2;aminoacylproline aminopeptidase;membrane-bound aminopeptidase P;APP2
Recombinant Proteins
- Human
- Mouse
- Rat
- Zebrafish
- Mammalian Cells
- HEK293
- C-His
- Human Cells
- E.coli
- His
- Non
- Flag
- Myc&DDK
- His&Fc&Avi
Involved Pathway
XPNPEP2 involved in several pathways and played different roles in them. We selected most pathways XPNPEP2 participated on our site, such as Protein digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with XPNPEP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein digestion and absorption | SLC3A1,CELA3A,MME,LOC780933,CPA2,ATP1A3,SLC36A1,PGA4,SLC1A1,CPB1 |
Protein Function
XPNPEP2 has several biochemical functions, for example, aminopeptidase activity,metal ion binding,metallopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by XPNPEP2 itself. We selected most functions XPNPEP2 had, and list some proteins which have the same functions with XPNPEP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| aminopeptidase activity | METAP2,PEPD,RNPEP,LNPEP,METAP2A,ENPEP,DPP9,ANPEP,DNPEP,Ctsl |
| metal ion binding | VPS18,GIT1,GFI1AB,HMGCL,ACSM2,ESYT1,ZNF670,GLRX3,NR2F1B,SETDB1A |
| metallopeptidase activity | MEP1A.2,PAPPA,NPSN,AMZ2,MMP30,ADAMTS12,MMP25,ADAM15,CLCA3,BMP1 |
Interacting Protein
XPNPEP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with XPNPEP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of XPNPEP2.
Resources
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References
- Banu, SK; Stanley, JA; et al. Identifying a Novel Role for X-prolyl Aminopeptidase (Xpnpep) 2 in CrVI-Induced Adverse Effects on Germ Cell Nest Breakdown and Follicle Development in Rats. BIOLOGY OF REPRODUCTION 92:-(2015).
- Wadelius, M; Marshall, SE; et al. Phenotype Standardization of Angioedema in the Head and Neck Region Caused by Agents Acting on the Angiotensin System. CLINICAL PHARMACOLOGY & THERAPEUTICS 96:477-481(2014).
