WNT8A

  • Official Full Name

    wingless-type MMTV integration site family, member 8A

  • Overview

    The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and may be implicated in development of early embryos as well as germ cell tumors. It encodes a protein which shows 81% amino acid identity to the mouse Wnt8A protein.

  • Synonyms

    WNT8A;wingless-type MMTV integration site family, member 8A;protein Wnt-8a;WNT8D;protein Wnt-8d

Recombinant Proteins

  • Mouse
  • Human
  • Chicken
  • Zebrafish
  • CHO
  • Human Cells
  • HEK293
  • Mammalian Cells
  • E.coli
  • Non
  • Strep II
  • DDK&Myc
  • His
  • Flag
  • Avi&Fc&His
Cat.# Product name Source (Host) Species Tag Protein Length Price
Wnt8a-619M Active Recombinant Mouse Wnt8a CHO Mouse Non Ala20-Trp354
WNT8A-209H Recombinant Human WNT8A, StrepII-tagged Human Cells Human Strep II 25-351, 327 a.a.
WNT8A-254H Recombinant Human WNT8A protein, MYC/DDK-tagged HEK293 Human DDK&Myc
WNT8A-7079C Recombinant Chicken WNT8A Mammalian Cells Chicken His
WNT8A-8586Z Recombinant Zebrafish WNT8A Mammalian Cells Zebrafish His
WNT8A-287HCL Recombinant Human WNT8A 293 Cell Lysate HEK293 Human Non
WNT8A-123H Active Recombinant Human WNT8A Protein E.coli Human
WNT8A-1342HFL Recombinant Full Length Human WNT8A Protein, C-Flag-tagged Mammalian Cells Human Flag Full L.
WNT8A-2049HFL Recombinant Full Length Human WNT8A protein, Flag-tagged Mammalian Cells Human Flag Full L.
WNT8A-2361H Recombinant Human WNT8A Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
WNT8A-2361H-B Recombinant Human WNT8A Protein Pre-coupled Magnetic Beads HEK293 Human
Wnt8a-7007M Recombinant Mouse Wnt8a Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc

    Involved Pathway

    WNT8A involved in several pathways and played different roles in them. We selected most pathways WNT8A participated on our site, such as Wnt signaling pathway,Hedgehog signaling pathway,Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with WNT8A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Melanogenesis FZD7A,WNT11B,FZD3,WNT5A,WNT4,POMC,WNT11,WNT3,PRKACAA,GNAI2B
    HTLV-I infection PIK3CG,SLC25A31,EGR2,KRAS,WNT3,HLA-DQA2,NFATC1,TLN1,HLA-DQB1,HLA-DOA
    Hedgehog signaling pathway PRKACBB,BMP4,CSNK1DA,WNT11B,WNT2,CSNK1G3,Shh,SKIA,SUFU,SHHB
    Proteoglycans in cancer TWIST1,WNT2B,AKT2,TGFB1,ROCK2,MSN,FZD5,CAV3,BRAF,ELK1
    Wnt signaling pathway PPP3R1,SKP1,WNT8B,DKK4,CAMK2G,FZD3,MAP3K7,PLCB4,MAPK8A,WNT2B
    Pathways in cancer GLI3,PTCH1,NKX3-1,PTGER2,RAF1,HGF,TRAF6,CXCL12,VEGFB,Flt3l
    Hippo signaling pathway APC2,FZD2,TCF7,CCND3,BMPR1A,WNT2B,PARD6A,PPP2CA,WNT8B,AREG
    Signaling pathways regulating pluripotency of stem cells STAT3,MYF5,ACVR1C,MEIS1,SKIL,SOX2,BMI1,ZFHX3,AXIN2,PIK3CG
    Basal cell carcinoma BMP4,STK36,Shh,AXIN1,WNT3,TCF7,WNT11,DVL3,TP53,FZD5

    Protein Function

    WNT8A has several biochemical functions, for example, frizzled binding,receptor agonist activity. Some of the functions are cooperated with other proteins, some of the functions could acted by WNT8A itself. We selected most functions WNT8A had, and list some proteins which have the same functions with WNT8A. You can find most of the proteins on our site.

    Function Related Protein
    frizzled binding SFRP1,WNT7B,ZNRF3,CTHRC1,FZD1,WNT5A,MYOC,WNT9B,NDP,WNT10B
    receptor agonist activity WNT4,VEGFA,WNT2,WNT7A,WNT10B,GAS6,WNT3A,WNT1,CXCL13,SFRP2

    Interacting Protein

    WNT8A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WNT8A here. Most of them are supplied by our site. Hope this information will be useful for your research of WNT8A.

    WNT8A Related Signal Pathway

    Resources

    Gene Families

    What Is Wingless-INT (WNT)

    Research Area

    Early Mesodermal Lineage Markers
    Wnt Ligands (Wnts)
    Ectodermal Lineage Markers
    Mesodermal Lineage Markers

    References

    • Choi, SC; Lee, H; et al. Cyclosporin A Induces Cardiac Differentiation but Inhibits Hemato-Endothelial Differentiation of P19 Cells. PLOS ONE 10:-(2015).
    • Stanganello, E; Hagemann, AIH; et al. Filopodia-based Wnt transport during vertebrate tissue patterning. NATURE COMMUNICATIONS 6:-(2015).

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