VSX2
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Official Full Name
visual system homeobox 2 -
Overview
This gene encodes a homeobox protein originally described as a retina-specific transcription factor. Mutations in this gene are associated with microphthalmia, cataracts and iris abnormalities. -
Synonyms
VSX2;visual system homeobox 2;C elegans ceh 10 homeo domain containing homolog , ceh 10 homeo domain containing homolog (C. elegans) , ceh 10 homeodomain containing homolog (C. elegans) , CHX10, HOX10;RET1;homeobox protein CHX10;ceh-10 homeodomain-
Recombinant Proteins
- Human
- Mouse
- Chicken
- Zebrafish
- Wheat Germ
- Mammalian Cell
- HEK293
- HEK293T
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| VSX2-1353H | Recombinant Human VSX2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| VSX2-18402M | Recombinant Mouse VSX2 Protein | Mammalian Cell | Mouse | His |
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| VSX2-6332C | Recombinant Chicken VSX2 | Mammalian Cell | Chicken | His |
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| VSX2-9029Z | Recombinant Zebrafish VSX2 | Mammalian Cell | Zebrafish | His |
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| VSX2-356HCL | Recombinant Human VSX2 cell lysate | Human | Non |
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| VSX2-10089M | Recombinant Mouse VSX2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| VSX2-10089M-B | Recombinant Mouse VSX2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| VSX2-1529H | Recombinant Human VSX2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| VSX2-1838HF | Recombinant Full Length Human VSX2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 361 amino acids |
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| Vsx2-890M | Recombinant Mouse Vsx2 Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
VSX2 involved in several pathways and played different roles in them. We selected most pathways VSX2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with VSX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
VSX2 has several biochemical functions, for example, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VSX2 itself. We selected most functions VSX2 had, and list some proteins which have the same functions with VSX2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sequence-specific DNA binding | NKX6.3,VDRB,GSX2,GATA1A,NR1D4A,RORA,GCM2,TBX5A,MKXA,FOXF1 |
Interacting Protein
VSX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VSX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of VSX2.
CDC37;ZDHHC17
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References
- Capowski, EE; Simonett, JM; et al. Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation. HUMAN MOLECULAR GENETICS 23:6332-6344(2014).
- Chassaing, N; Causse, A; et al. Molecular findings and clinical data in a cohort of 150 patients with anophthalmia/microphthalmia. CLINICAL GENETICS 86:326-334(2014).
