VNN1
-
Official Full Name
vanin 1 -
Overview
This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24. -
Synonyms
VNN1;vanin 1;pantetheinase;Tiff66;HDLCQ8;High density lipoprotein cholesterol level quantitative trait locus 8, included;Pantetheine hydrolase;V-1;Vanin-1;Vannin 1;Vascular non inflammatory molecule 1;Vascular non-inflammatory molecule 1;VNN 1;VNN1_HUMAN
Recombinant Proteins
- Human
- Mouse
- Chicken
- Cattle
- Rat
- HEK293
- E.coli
- CHO
- Mammalian Cells
- Human Cells
- His
- His&T7
- Fc
- Non
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| VNN1-3229H | Active Recombinant Human VNN1 protein, His-tagged | HEK293 | Human | His | Met1-Ser490 | |
| VNN1-3668H | Recombinant Human VNN1, His-tagged | E.coli | Human | His | 302-513aa | |
| VNN1-1084H |
Active Recombinant Human VNN1 Protein, His-tagged
|
CHO | Human | His | Gln22-Ser490 |
|
| Vnn1-2560M | Recombinant Mouse Vnn1 protein(Met1-Ser487), His-tagged | HEK293 | Mouse | His | Met1-Ser487 |
|
| VNN1-3349C | Recombinant Chicken VNN1 | Mammalian Cells | Chicken | His |
|
|
| VNN1-7930C | Recombinant Cattle VNN1 protein, His & T7-tagged | E.coli | Cattle | His&T7 | Leu216~Gly469 |
|
| VNN1-7931H | Recombinant Human VNN1 protein, His-tagged | E.coli | Human | His | Leu36~Leu223 |
|
| Vnn1-7932M | Recombinant Mouse Vnn1 protein, His-tagged | E.coli | Mouse | His | Val390~Ile503 |
|
| Vnn1-7933R | Recombinant Rat Vnn1 protein, His & T7-tagged | E.coli | Rat | His&T7 | Ser22~Pro328 |
|
| VNN1-933M | Recombinant Mouse VNN1 Protein, Fc-tagged | HEK293 | Mouse | Fc | 1-487 a.a. |
|
| VNN1-1583MCL | Recombinant Mouse VNN1 cell lysate | Human Cells | Mouse | Non |
|
|
| VNN1-2442HCL | Recombinant Human VNN1 cell lysate | Human Cells | Human | Non |
|
|
| VNN1-2671H | Active Recombinant Human VNN1 protein, His-tagged | HEK293 | Human | His | Gln22-Ser490 |
|
| VNN1-572H | Recombinant Human VNN1 Protein, His-tagged | E.coli | Human | His | Gln22-Gly491 |
|
| VNN1-6674H | Recombinant Human VNN1 Protein (Ser302-Trp513), N-His tagged | E.coli | Human | His | Ser302-Trp513 |
|
Involved Pathway
VNN1 involved in several pathways and played different roles in them. We selected most pathways VNN1 participated on our site, such as Pantothenate and CoA biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with VNN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Pantothenate and CoA biosynthesis | PANK1,PPCS,VNN2,PANK4,AASDHPPT,BCAT2,BCAT1,DPYD,PANK1B,PANK3 |
Protein Function
VNN1 has several biochemical functions, for example, GPI anchor binding,pantetheine hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by VNN1 itself. We selected most functions VNN1 had, and list some proteins which have the same functions with VNN1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| pantetheine hydrolase activity | VNN2,VNN3 |
| GPI anchor binding | MPPE1,THY1,DPEP1,NIPAL1,CEACAM5 |
Interacting Protein
VNN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VNN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of VNN1.
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