VIPR1
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Official Full Name
vasoactive intestinal peptide receptor 1 -
Overview
This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene. -
Synonyms
VIPR1;vasoactive intestinal peptide receptor 1;vasoactive intestinal polypeptide receptor 1;HVR1;RDC1;VIP and PACAP receptor 1;VPAC1;VPAC1R;VIP receptor, type I;PACAP type II receptor;pituitary adenylate cyclase activating polypeptide receptor,
Recombinant Proteins
- Mouse
- Chicken
- Rhesus macaque
- Rat
- Human
- Carassius auratus (Goldfish)
- Meleagris gallopavo (Wild turkey)
- Sus scrofa (Pig)
- Mus musculus
- Mammalian Cell
- E.coli
- E.coli expression system
- HEK293
- His
- His&T7
- Non
- His&Fc&Avi
- His&Flag
Involved Pathway
VIPR1 involved in several pathways and played different roles in them. We selected most pathways VIPR1 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with VIPR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | PRLR,THRAA,GRM8,MCHR2,CHRNE,S1PR5A,GRIN2BB,GRIK2,TACR3L,GZMA |
Protein Function
VIPR1 has several biochemical functions, for example, protein binding,vasoactive intestinal polypeptide receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by VIPR1 itself. We selected most functions VIPR1 had, and list some proteins which have the same functions with VIPR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | RPS14,KRT6A,EPN2,SEPT9,SNRPD3,SLC9A7,TRIM24,SETD2,RAD9B,SH3BP2 |
| vasoactive intestinal polypeptide receptor activity | VIPR1B,ADCYAP1R1,VIPR2,ADCYAP1R1A,GHRHRL |
Interacting Protein
VIPR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VIPR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of VIPR1.
HLA-B;VIP;CALM1;TINF2
Resources
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References
- Paladini, F; Cocco, E; et al. Age-dependent association of idiopathic achalasia with vasoactive intestinal peptide receptor 1 gene. NEUROGASTROENTEROLOGY AND MOTILITY 21:597-602(2009).
- Shibata, M; Hisajima, T; et al. Morphological relationships between peptidergic nerve fibers and immunoglobulin A-producing lymphocytes in the mouse intestine. BRAIN BEHAVIOR AND IMMUNITY 22:158-166(2008).
