VAMP7
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Official Full Name
vesicle-associated membrane protein 7 -
Overview
This gene encodes a transmembrane protein that is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family. The encoded protein localizes to late endosomes and lysosomes and is involved in the fusion of transport vesicles to their target membranes. Alternate splicing results in multiple transcript variants. -
Synonyms
VAMP7;vesicle-associated membrane protein 7;SYBL1, synaptobrevin like 1;TI VAMP;VAMP 7;synaptobrevin-like 1;tetanus-insensitive VAMP;synaptobrevin-like protein 1;tetanus neurotoxin-insensitive VAMP;SYBL1;TIVAMP;VAMP-7;TI-VAMP;FLJ53045;FLJ53
Recombinant Proteins
- Mouse
- Chicken
- Rhesus macaque
- Rat
- Human
- Mammalian Cell
- E. coli
- E.coli
- HEK293
- His
- His&Fc&Avi
Involved Pathway
VAMP7 involved in several pathways and played different roles in them. We selected most pathways VAMP7 participated on our site, such as SNARE interactions in vesicular transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with VAMP7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| SNARE interactions in vesicular transport | STX5,BNIP1,BET1,SEC22B,STX18,GOSR1,VAMP5,SNAP23.2,VAMP3,SYBL1 |
Protein Function
VAMP7 has several biochemical functions, for example, SNAP receptor activity,SNARE binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VAMP7 itself. We selected most functions VAMP7 had, and list some proteins which have the same functions with VAMP7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| SNARE binding | NBAS,STX2A,GABARAPL2,TNFAIP2A,STX5A,STX1A,ANKRD27,UVRAG,GOSR2,SEC22C |
| SNAP receptor activity | SYBL1,STX2,SEC22BB,VAMP1,STX11A,STX11B.2,STX18,GOSR2,SNAP25B,STX11B.1 |
| syntaxin binding | SYT3,CAV1,VPS52,SYTL2,NAPAB,SYT5B,DOC2B,STXBP1,SYTL4,STXBP5L |
| protein binding | SERPINF2,ACTN2,MT1A,RSU1,RASAL2,HIST1H2AM,SMARCC1,ERG,MCC,HOXC4 |
Interacting Protein
VAMP7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VAMP7 here. Most of them are supplied by our site. Hope this information will be useful for your research of VAMP7.
N/A;STX17;Stx7;Vti1b;Hmga2;Lamp1
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References
- Schena, F; Volpi, S; et al. Dependence of Immunoglobulin Class Switch Recombination in B Cells on Vesicular Release of ATP and CD73 Ectonucleotidase Activity. CELL REPORTS 3:1824-1831(2013).
- Vacca, M; Albania, L; et al. Alternative splicing of the human gene SYBL1 modulates protein domain architecture of longin VAMP7/TI-VAMP, showing both non-SNARE and synaptobrevin-like isoforms. BMC MOLECULAR BIOLOGY 12:-(2011).
