Ubc9
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Official Full Name
ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) -
Overview
Human Ubquitin Conjugating Enzyme 9 (Ubc9) is a member of the E2 family and is specific for the conjugation of SUMO to a variety of target proteins. SUMO conjugation to target proteins is mediated by a different, but analogous, pathway to ubiquitinylation. This E2 is unusual in that it interacts directly with protein substrates that are modified by sumolyation, and may play a role in substrate recognition. Ubc9 can mediate the conjugation of SUMO-1 to a variety of proteins including RanGAP1, IκBα, and PML without the requirement of an E3 ligase. -
Synonyms
SUMO-conjugating enzyme UBC9;EC 6.3.2.-;SUMO-protein ligase;Ubiquitin-conjugating enzyme E2 I;Ubiquitin-protein ligase I;Ubiquitin carrier protein I;Ubiquitin carrier protein 9;p18;UBC9;C358B7.1;P18;UBCE9;SUMO-1-protein ligase;ubiquitin carrier protein;ubiquitin conjugating enzyme 9
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| UBC9-3524H | Recombinant Human UBC9, GST-tagged | E.coli | Human | GST | 0-184AA |
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| UBC9-3407H | Recombinant Human UBC9 protein, His-tagged | E.coli | Human | His | 1-184 aa |
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| Ubc9-14H | Recombinant Human Ubiquitin Conjugating Enzyme 9, His | E.coli | Human | His |
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| UBC9-3525H | Recombinant Human UBE2I Protein, 1-158aa, GST-tagged | E. coli | Human | GST | 1-158 a.a. |
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Involved Pathway
Ubc9 involved in several pathways and played different roles in them. We selected most pathways Ubc9 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Ubc9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
Ubc9 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by Ubc9 itself. We selected most functions Ubc9 had, and list some proteins which have the same functions with Ubc9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
Ubc9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ubc9 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ubc9.
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