USP30
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Official Full Name
ubiquitin specific peptidase 30 -
Overview
USP30, a member of the ubiquitin-specific protease family (see USP1, MIM 603478), is a novel mitochondrial;deubiquitinating (DUB) enzyme (Nakamura and Hirose, 2008 (PubMed 18287522)). -
Synonyms
USP30;ubiquitin specific peptidase 30;ubiquitin specific protease 30;ubiquitin carboxyl-terminal hydrolase 30;FLJ40511;MGC10702;ub-specific protease 30;ubiquitin thioesterase 30;deubiquitinating enzyme 30;ubiquitin thiolesterase 30;ubiquitin-spe
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- Zebrafish
- Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
- zebrafish
- E.coli
- Insect Cell
- Mammalian Cell
- E.coli expression system
- Insect Cells
- HEK293
- His
- Non
- GST
- SUMO
- His&Fc&Avi
Involved Pathway
USP30 involved in several pathways and played different roles in them. We selected most pathways USP30 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with USP30 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
USP30 has several biochemical functions, for example, cysteine-type endopeptidase activity,ubiquitin-specific protease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by USP30 itself. We selected most functions USP30 had, and list some proteins which have the same functions with USP30. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ubiquitin-specific protease activity | USP25,CYLD,JOSD2,USP42,STAMBP,USP9X,OTUD3,USP4,USP46,FAM105B |
| cysteine-type endopeptidase activity | USP3,CTSO,USP45,USP25,LGMN,CTLA2B,USP1,USP28,CASPBL,CASP6L1 |
Interacting Protein
USP30 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USP30 here. Most of them are supplied by our site. Hope this information will be useful for your research of USP30.
TIMM8A;SS18L1;SF3A1;QKI;CLPB;MPND
Resources
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References
- Feng, AP; He, YM; et al. Expression of USP15, T beta R-I and Smad7 in psoriasis. JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY-MEDICAL SCIENCES 34:415-419(2014).
- Wang, X; Stafford, W; et al. The 19S Deubiquitinase Inhibitor b-AP15 Is Enriched in Cells and Elicits Rapid Commitment to Cell Death. MOLECULAR PHARMACOLOGY 85:932-945(2014).
