USH2A
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Official Full Name
Usher syndrome 2A (autosomal recessive, mild) -
Overview
This gene encodes a protein that contains laminin EGF motifs, a pentaxin domain, and many fibronectin type III motifs. The protein is found in the basement membrane, and may be important in development and homeostasis of the inner ear and retina. Mutations within this gene have been associated with Usher syndrome type IIa and retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
USH2A;Usher syndrome 2A (autosomal recessive, mild);USH2;usherin;RP39;dJ1111A8.1;US2;Usher syndrome type IIa protein;Usher syndrome type-2A protein;OTTHUMP00000035145;OTTHUMP00000063383
Recombinant Proteins
- Mouse
- Rat
- Mammalian Cell
- Yeast
- HEK293
- E.coli
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| USH2A-17894M | Recombinant Mouse USH2A Protein | Mammalian Cell | Mouse | His |
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| USH2A-6464R | Recombinant Rat USH2A Protein | Mammalian Cell | Rat | His |
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| Ush2A-4322M | Recombinant Mouse Ush2A protein, His-tagged | Yeast | Mouse | His | 265-517aa |
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| USH2A-6120R | Recombinant Rat USH2A Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| USH2A-6120R-B | Recombinant Rat USH2A Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Ush2A-6473M | Recombinant Mouse Ush2A protein, His-tagged | E.coli | Mouse | His | 265-517aa |
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| USH2A-9942M | Recombinant Mouse USH2A Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| USH2A-9942M-B | Recombinant Mouse USH2A Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
USH2A involved in several pathways and played different roles in them. We selected most pathways USH2A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with USH2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
USH2A has several biochemical functions, for example, collagen binding,myosin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by USH2A itself. We selected most functions USH2A had, and list some proteins which have the same functions with USH2A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein homodimerization activity | ECE1,EPHX2,BCL2A,KLHL7,GAMT,CEBPA,CD8A,DGAT2,TBC1D22A,ERCC5 |
| collagen binding | SERPINH2,NID2,GP6,ITGA1,SERPINH1B,SRGN,CTSS,ANTXR1,SERPINH1,HSD17B12 |
| protein binding | BANK1,COL10A1,AP1B1,ERH,CYTIP,NOX5,MLH1,UBE2Z,HGS,GNG12 |
| myosin binding | STX4A,SMYD1B,DMD,ARFGEF2,KIRREL,ACTA1,CALM,ACTC1,CALD1,VEZT |
Interacting Protein
USH2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USH2A here. Most of them are supplied by our site. Hope this information will be useful for your research of USH2A.
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