UPP2

  • Official Full Name

    uridine phosphorylase 2
  • Synonyms

    UPP2;uridine phosphorylase 2;UDRPASE2;UP2;UPASE2;Liver specific uridine phosphorylase;UPase 2;UPP 2;UPP2_HUMAN;UrdPase 2;uridine phosphorylase-2;liver-specific uridine phosphorylase

Recombinant Proteins

  • Human
  • Zebrafish
  • Mouse
  • E.coli
  • Mammalian Cell
  • HEK293
  • HEK293T
  • Wheat Germ (in vitro)
  • GST
  • His
  • His&T7
  • Non
  • Flag
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
UPP2-3604H Recombinant Human UPP2, GST-tagged E.coli Human GST 1-317aa
UPP2-10493Z Recombinant Zebrafish UPP2 Mammalian Cell Zebrafish His
Upp2-1295M Recombinant Mouse Upp2 protein, His & T7-tagged E.coli Mouse His&T7 Met1~Ser320
UPP2-493HCL Recombinant Human UPP2 293 Cell Lysate HEK293 Human Non
UPP2-15HFL Recombinant Human UPP2 Protein, Full Length, C-Flag tagged HEK293T Human Flag Full L. Full Length
UPP2-20HFL Recombinant Human UPP2 Protein, Full Length, N-GST tagged Wheat Germ (in vitro) Human GST Full L. Full Length
Upp2-6849M Recombinant Mouse Upp2 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK

    Involved Pathway

    UPP2 involved in several pathways and played different roles in them. We selected most pathways UPP2 participated on our site, such as Drug metabolism - other enzymes,Fluoropyrimidine Activity,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with UPP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism of nucleotides ADSS,DTYMK,TM9SF1,ADSL,AK8,NUDT5,DPYS,GLRX,NUDT18,NUDT1
    Pyrimidine catabolism DPYD,TYMP,PROZA,DPYS,DPYDA.1
    Pyrimidine salvage reactions DCK
    Drug metabolism - other enzymes UGT1AB,NAT1,GUSB,TPMT,CES2,UCK2B,UGT2A3,UGT1A7C,Ces2c,IMPDH2
    Pyrimidine metabolism NME5,PNP,NUDT2,UCK2,ENTPD6,POLE,DPYD,UMPS,TXNRD3,DCTPP1
    Metabolic pathways UCK1,GALNTL1,ALDOCB,UGT1A6A,DNMT3A,PIGM,AMD1,GGT5,PRODH2,HADHB
    Metabolism SLC44A5B,DSEL,ST3GAL3A,ARSE,ABCA1,ETFA,PDZD11,SACM1LA,MED31,DAO
    Fluoropyrimidine Activity DPYD,CES1,DPYS,TYMP,DHFR,SLC22A7

    Protein Function

    UPP2 has several biochemical functions, for example, protein binding,uridine phosphorylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UPP2 itself. We selected most functions UPP2 had, and list some proteins which have the same functions with UPP2. You can find most of the proteins on our site.

    Function Related Protein
    uridine phosphorylase activity UPP1
    protein binding PPARD,NOP58,SH3GL1,APOL1,HIPK1,BFSP2,DBNL,LSM11,MSX2,SERPINB3C

    Interacting Protein

    UPP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UPP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of UPP2.

    SIAH1

    Resources

    References

    • Ma, GY; Zhang, JZ; et al. Toxoplasma gondii: Proteomic analysis of antigenicity of soluble tachyzoite antigen. EXPERIMENTAL PARASITOLOGY 122:41-46(2009).
    • Tokunaga, Y; Sasaki, H; et al. Clinical role of orotate phosphoribosyl transferase and dihydropyrimidine dehydrogenase in colorectal cancer treated with postoperative fluoropyrimidine. SURGERY 141:346-353(2007).
    • Liu, MP; Cao, DL; et al. Expression, characterization, and detection of human uridine phosphorylase and identification of variant uridine phosphorolytic activity in selected human tumors. CANCER RESEARCH 58:5418-5424(1998).

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