UGT2B17
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Official Full Name
UDP glucuronosyltransferase 2 family, polypeptide B17 -
Overview
This gene encodes a member of the uridine diphosphoglucuronosyltransferase protein family. The encoded enzyme catalyzes the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a diverse array of substrates including steroid hormones and lipid-soluble drugs. This process, known as glucuronidation, is an intermediate step in the metabolism of steroids. Copy number variation in this gene is associated with susceptibility to osteoporosis. -
Synonyms
UGT2B17;UDP glucuronosyltransferase 2 family, polypeptide B17;UDP glycosyltransferase 2 family, polypeptide B17;UDP-glucuronosyltransferase 2B17;C19 steroid specific UDP glucuronosyltransferase;C19 steroid specific UDPGT;UDB17;UDP glucuronosyltransferase 2B17;UDPGT 2B17;C19-steroid-specific UDPGT;UDP glycosyltransferase 2 family, member B17;UDP-glucuronyltransferase, family 2, beta-17;C19-steroid-specific UDP-glucuronosyltransferase;UDPGT2B17
Recombinant Proteins
- Rat
- Mus musculus
- Human
- Mammalian Cell
- E.coli expression system
- In vitro E. coli expression system
- HEK293
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| UGT2B17-6435R | Recombinant Rat UGT2B17 Protein | Mammalian Cell | Rat | His |
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| RFL17799MF | Recombinant Full Length Mouse Udp-Glucuronosyltransferase 2B17(Ugt2B17) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length of Mature Protein (24-530) |
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| RFL17834HF | Recombinant Full Length Human Udp-Glucuronosyltransferase 2B17(Ugt2B17) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length of Mature Protein (24-530aa) |
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| RFL30827RF | Recombinant Full Length Rat Udp-Glucuronosyltransferase 2B17(Ugt2B17) Protein, His-Tagged | E.coli expression system | Rat | His | Full L. Full Length of Mature Protein (24-530) |
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| UGT2B17-173H | Recombinant Human UGT2B17 Full Length Transmembrane protein, His-tagged | In vitro E. coli expression system | Human | His | Full L. 24-530aa |
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| UGT2B17-6091R | Recombinant Rat UGT2B17 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| UGT2B17-6091R-B | Recombinant Rat UGT2B17 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
UGT2B17 involved in several pathways and played different roles in them. We selected most pathways UGT2B17 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with UGT2B17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
UGT2B17 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by UGT2B17 itself. We selected most functions UGT2B17 had, and list some proteins which have the same functions with UGT2B17. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
UGT2B17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UGT2B17 here. Most of them are supplied by our site. Hope this information will be useful for your research of UGT2B17.
Resources
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References
- Izukawa, T; Nakajima, M; et al. Quantitative Analysis of UDP-Glucuronosyltransferase (UGT) 1A and UGT2B Expression Levels in Human Livers. DRUG METABOLISM AND DISPOSITION 37:1759-1768(2009).
- Chouinard, S; Yueh, MF; et al. Inactivation by UDP-glucuronosyltransferase enzymes: The end of androgen signaling. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 109:247-253(2008).
