UFD1L
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Official Full Name
ubiquitin fusion degradation 1 like -
Overview
Ubiquitin fusion degradation protein 1 homolog is a protein that in humans is encoded by the UFD1L gene. -
Synonyms
UFD1L;ubiquitin fusion degradation 1 like (yeast);ubiquitin fusion degradation 1 like;ubiquitin fusion degradation protein 1 homolog;UFD1;UB fusion protein 1
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Zebrafish
- Chicken
- Rat
- E.coli
- Mammalian Cell
- HEK293
- His
- Non
- GST
- His&Fc&Avi
Involved Pathway
UFD1L involved in several pathways and played different roles in them. We selected most pathways UFD1L participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with UFD1L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein processing in endoplasmic reticulum | HSPA4L,SSR3,SELS,RAD23A,UBE2E3,UBE2E1,DNAJB1A,MAN1C1,DNAJB1B,RRBP1 |
Protein Function
UFD1L has several biochemical functions, for example, K48-linked polyubiquitin binding,protein binding,protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UFD1L itself. We selected most functions UFD1L had, and list some proteins which have the same functions with UFD1L. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein complex binding | RPH3A,UGT1A6A,PPIB,GIT2,SLC25A3,SHANK1,TULP3,SKIL,AP2B1,MLC1 |
| receptor binding | PVRL1B,SERPINE2,PVRL4,P2RX7,LBP,NRG2B,HCK,HLA-G,MYO1C,NPPC |
| K48-linked polyubiquitin binding | IKBKE,UBXN1,VCP |
| protein binding | C22orf28,SUSD2,PLEKHB1,ZNF193,BTN3A1,TBC1D17,FAM46B,MAMSTR,STX6,GRIK3 |
| ubiquitin-specific protease activity | USP10,USP8,USP34,ATXN3L,USP9X,USP9,OTUD7A,BRCC3,UCHL5,VCPIP1 |
Interacting Protein
UFD1L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UFD1L here. Most of them are supplied by our site. Hope this information will be useful for your research of UFD1L.
NPLOC4;VCP;FAF1;LRRK2;Map3k1;UBL4A;CHM;USP13;VCPIP1;F13A1;A2M;IGHM;TP53;HSPB1;NGFR;PIK3CA;MASP1
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References
- Seguin, SJ; Morelli, FF; et al. Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly. CELL DEATH AND DIFFERENTIATION 21:1838-1851(2014).
- Hsu, CW; Yu, JS; et al. Secretome Profiling of Primary Cells Reveals That THBS2 Is a Salivary Biomarker of Oral Cavity Squamous Cell Carcinoma. JOURNAL OF PROTEOME RESEARCH 13:4796-4807(2014).
