UCK1
-
Official Full Name
uridine-cytidine kinase 1 -
Overview
This gene encodes a uridine-cytidine kinase that catalyzes the phosphorylation of uridine and cytidine to uridine;monophosphate (UMP) and cytidine monophosphate (CMP) but not the phosphorylation of deoxyribonucleosides or purine;ribonucleosides. This enzyme can also phosphorylate uridine and cytidine analogs and uses both ATP and GTP as a;phosphate donor. Alternative splicing results in multiple splice variants encoding distinct isoforms. -
Synonyms
UCK1;uridine-cytidine kinase 1;FLJ12255;URK1;Cytidine monophosphate kinase;Cytidine monophosphokinase 1;Cytidylate kinase;Deoxycytidylate kinase;OTTHUMP00000022400;OTTHUMP00000022401;OTTHUMP00000022403;OTTHUMP00000022404;RP11-334J6.5;UCK 1;UCK1_HUMAN;UMP-CMP kinase;Uridine monophosphokinase 1
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- Mammalian cells
- HEK293T
- GST
- His
- Myc&DDK
- Non
- Flag
- His&Fc&Avi
- His&SUMO
- His&GST
Involved Pathway
UCK1 involved in several pathways and played different roles in them. We selected most pathways UCK1 participated on our site, such as Pyrimidine metabolism,Drug metabolism - other enzymes,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with UCK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | CMPK1,NDUFC1,PLA2G6,DHDPSL,OAT,AMPD1,DPYS,LPCAT2,BAAT,PIGA |
| Drug metabolism - other enzymes | NAT,GMPS,CES2,UGT1A7C,UPP2,UGT1A1,UGT1A6A,XDH,UGT1A6B,GUSB |
| Pyrimidine metabolism | NT5C1AA,POLR3GLB,CANT1A,CANT1B,TXNRD3,POLR2GL,POLR3GL,PNP5A,TYMP,NUDT2 |
Protein Function
UCK1 has several biochemical functions, for example, ATP binding,nucleoside kinase activity,uridine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UCK1 itself. We selected most functions UCK1 had, and list some proteins which have the same functions with UCK1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| nucleoside kinase activity | UCK2B,DGUOK,UCK2A,TK1,UCK2,DCK |
| uridine kinase activity | UCK2B,UCK2A,CMPK1,UCK2,UCKL1,UPRT,UCKL1A |
| ATP binding | UBE2D1B,KIF23,ILF2,DHX9,CHST13,NTRK3,TAF1,ABCG2D,WEE1,SBK1 |
Interacting Protein
UCK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UCK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UCK1.
ezrA;PLA2G12A
Resources
Related Services
Related Products
References
