UBN1
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Official Full Name
ubinuclein 1 -
Synonyms
UBN1;ubinuclein 1;ubinuclein-1;HIRA-binding protein;ubiquitously expressed nuclear protein;VT;VT4
Recombinant Proteins
- Mouse
- Chicken
- Rhesus macaque
- Zebrafish
- Human
- Mammalian Cell
- E.coli
- HEK293
- His
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| UBN1-17751M | Recombinant Mouse UBN1 Protein | Mammalian Cell | Mouse | His |
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| UBN1-3551C | Recombinant Chicken UBN1 | Mammalian Cell | Chicken | His |
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| UBN1-5078R | Recombinant Rhesus monkey UBN1 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| UBN1-5993Z | Recombinant Zebrafish UBN1 | Mammalian Cell | Zebrafish | His |
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| UBN1-301479H | Recombinant Human UBN1 protein, GST-tagged | E.coli | Human | GST | Met592-His791 |
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| UBN1-4891R | Recombinant Rhesus Macaque UBN1 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| UBN1-4891R-B | Recombinant Rhesus Macaque UBN1 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| UBN1-9853M | Recombinant Mouse UBN1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| UBN1-9853M-B | Recombinant Mouse UBN1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
UBN1 involved in several pathways and played different roles in them. We selected most pathways UBN1 participated on our site, such as Cellular Senescence,Cellular responses to stress,DNA Damage/Telomere Stress Induced Senescence, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| DNA Damage/Telomere Stress Induced Senescence | TINF2,TERF2IP,POT1A,CABIN1,HMGA1-RS1,POT1,HMGA1B,HMGA1,HIST1H1C,ACD |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | HMGA1-RS1,HIST1H1C,HIST1H1E,HIST1H1A,H1F0,HMGA1B,ASF1A,CABIN1,EP400,HIST1H1D |
| Cellular Senescence | MINK1,RBBP4,RBBP7,ASF1A,PHC3,HIST4H4,KAT5,TERF2,HIST3H2BB,TNIK |
| Cellular responses to stress | HTATIP,UVRAG,ACD,HIF1AL,HDAC6,LC3,CDKN2A,ATG4A,SCMH1,C11orf73 |
Protein Function
UBN1 has several biochemical functions, for example, DNA binding,transcription factor activity, sequence-specific DNA binding,transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UBN1 itself. We selected most functions UBN1 had, and list some proteins which have the same functions with UBN1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | POLR1E,HIST2H4A,HIST2H2BE,NKX2-3,ZNF7,NAT14,PAX2A,HOMEZ,RAD54B,GBX1 |
| transcription factor binding | TFDP1B,ATF7,PDX1,SP100,HDAC1,PIM1,EGR1,NIF3L1,PPP1R13BB,SOX8 |
| transcription factor activity, sequence-specific DNA binding | RORA,HOXB3A,ZNF174,ETV5B,POU4F1,FBXW7,NFKB2,KLF9,TFDP1,SOX4 |
Interacting Protein
UBN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UBN1.
Ywhae
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References
- Pchelintsev, NA; McBryan, T; et al. Placing the HIRA Histone Chaperone Complex in the Chromatin Landscape. CELL REPORTS 3:1012-1019(2013).
- Tang, Y; Puri, A; et al. Identification of an Ubinuclein 1 Region Required for Stability and Function of the Human HIRA/UBN1/CABIN1/ASF1a Histone H3.3 Chaperone Complex. BIOCHEMISTRY 51:2366-2377(2012).
