UBE2O

  • Official Full Name

    ubiquitin-conjugating enzyme E2O

  • Overview

    Ubiquitin-conjugating enzyme E2 O is a protein that in humans is encoded by the UBE2O gene.

  • Synonyms

    UBE2O;ubiquitin-conjugating enzyme E2O;ubiquitin-conjugating enzyme E2 O;E2 230K;EC=6.3.2.19;FLJ12878;KIAA1734;Likely Ortholog of Mouse Ubiquitin Conjugating Enzyme;RP23 193A16.5;UBE2O_HUMAN;Ubiquitin carrier protein O;Ubiquitin conjugating enzyme E2 O;Ubiquitin conjugating enzyme E2 of 230 kDa;ubiquitin conjugating enzyme E2O;Ubiquitin protein ligase O;Ubiquitin-conjugating enzyme E2 of 230 kDa;Ubiquitin-conjugating enzyme E2-230K;Ubiquitin-protein ligase O;E2-230K

Recombinant Proteins

  • Human
  • Mouse
  • E.coli
  • Insect Cell
  • Mammalian Cell
  • HEK293T
  • HEK293
  • His
  • GST
  • Non
  • His&Strep
  • Myc&DDK
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
UBE2O-3541H Recombinant Human UBE2O, His-tagged E.coli Human His 48-339aa
UBE2O-651H Active Recombinant Human UBE2O Protein, GST-tagged Insect Cell Human GST
UBE2O-17727M Recombinant Mouse UBE2O Protein Mammalian Cell Mouse His
UBE2O-1871HCL Recombinant Human UBE2O cell lysate Human Non
UBE2O-0408H Recombinant Human UBE2O Protein (A2-K1292), His/Strep tagged Insect Cell Human His&Strep A2-K1292
UBE2O-0409H Recombinant Human UBE2O Protein (A2-K1292), Tag Free Insect Cell Human Non A2-K1292
Ube2o-6795M Recombinant Mouse Ube2o Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
UBE2O-9834M Recombinant Mouse UBE2O Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
UBE2O-9834M-B Recombinant Mouse UBE2O Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    UBE2O involved in several pathways and played different roles in them. We selected most pathways UBE2O participated on our site, such as Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2O were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ubiquitin mediated proteolysis CUL1,UBE2KA,ITCHA,ANAPC13,UBA6,UBE4A,SMURF1,HERC4,SIAH2L,UBE2L3B

    Protein Function

    UBE2O has several biochemical functions, for example, ATP binding,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2O itself. We selected most functions UBE2O had, and list some proteins which have the same functions with UBE2O. You can find most of the proteins on our site.

    Function Related Protein
    ubiquitin conjugating enzyme activity UBE2D2,UBE2H,UBE2E3,UBE2L3,UBE2V1,UBE2J2,UBE2QL1,UBE2D4,UBE2Q1,UBE2Q2
    poly(A) RNA binding UBE2N,RPUSD3,TFB2M,DUSP11,DHX36,LRPPRC,TFAM,SRSF3,FAM32A,THRAP3
    ubiquitin protein ligase activity RNF122,RNF24,MED21,MSL2A,WWP2,RBX1,C18orf25,BRAP,RAG2,NHLRC1
    ATP binding DSTYK,SCYL2,CLPB,H1FNT,RPS6KA3A,FGFR1B,DHX29,ATP2B4,ACSM2,ATP2A2
    protein binding UBASH3B,PCBP2,ZC4H2,GNG12,ARIH1,PRPS1,TRIM21,RAD9A,SGOL2,KCNQ4
    ubiquitin protein ligase binding CUL1B,NLK,JKAMP,RPA3,TRIB3,FZD8,GABARAPL2,SMAD3,AKTIP,SMAD5
    ubiquitin-protein transferase activity UBR4,UBE2D2,TRIM62,UBE2R2,FBXL3,BIRC2,RNF139,CDC23,MYLIP,ANKIB1A

    Interacting Protein

    UBE2O has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2O here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2O.

    APPL1;Smad6;tat;UBE2V1;Smad7;SMAD6;BAP1;Rnf111;RLIM;al554633_hum_protein;TRIM27;RPL12

    Resources

    References

    • Mashtalir, N; Daou, S; et al. Autodeubiquitination Protects the Tumor Suppressor BAP1 from Cytoplasmic Sequestration Mediated by the Atypical Ubiquitin Ligase UBE2O. MOLECULAR CELL 54:392-406(2014).
    • Yu, J; Feng, L; et al. Vitreous proteomic analysis of idiopathic epiretinal membranes. MOLECULAR BIOSYSTEMS 10:2558-2566(2014).

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