SYP

  • Official Full Name

    Synaptophysin
  • Overview

    Defects in SYP are the cause of mental retardation X-linked SYP-related (MRXSYP) [MIM:300802]. Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period.
  • Synonyms

    Major synaptic vesicle protein P38;Syn p38;Synaptophysin;SYP;SYPH;SypI

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Rat
  • Bovine
  • Spermophilus citellus (European suslik) (Citellus citellus)
  • E.coli
  • Wheat Germ
  • Mammalian Cell
  • HEK293
  • Mouse
  • E.coli expression system
  • In vitro E. coli expression system
  • In Vitro Cell Free System
  • His
  • Non
  • N-SUMO & N-His
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
SYP-3076H Recombinant Human SYP, His-tagged E.coli Human His 50-313aa
SYP-31490TH Recombinant Human SYP Wheat Germ Human Non 313 amino acids
SYP-4587R Recombinant Rhesus monkey SYP Protein, His-tagged Mammalian Cell Rhesus macaque His
SYP-5874R Recombinant Rat SYP Protein Mammalian Cell Rat His
SYP-1313HCL Recombinant Human SYP 293 Cell Lysate HEK293 Human Non
CPB-922MH Mouse Anti-Human Synaptophysin Monoclonal Antibody Mouse Human Non
RFL17140RF Recombinant Full Length Rat Synaptophysin(Syp) Protein, His-Tagged E.coli expression system Rat His Full L. Full Length (1-307)
RFL20132BF Recombinant Full Length Bovine Synaptophysin(Syp) Protein, His-Tagged E.coli expression system Bovine His Full L. Full Length (1-313)
RFL33831SF Recombinant Full Length Spermophilus Citellus Synaptophysin(Syp) Protein, His-Tagged E.coli expression system Spermophilus citellus (European suslik) (Citellus citellus) His Full L. Full Length (1-307)
RFL735HF Recombinant Full Length Human Synaptophysin(Syp) Protein, His-Tagged E.coli expression system Human His Full L. Full Length of Mature Protein (224-313)
Syp-0148R Recombinant Rat Syp Full Length Transmembrane protein, His-tagged In vitro E. coli expression system Rat His Full L. 1-307aa
SYP-2596H Recombinant Human SYP protein(228-313 aa), N-SUMO & N-His-tagged E.coli Human N-SUMO & N-His 228-313 aa
SYP-2747H Recombinant Human SYP Protein, His-tagged E.coli Human His Glu50-Phe106
SYP-4403R Recombinant Rhesus Macaque SYP Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
SYP-4403R-B Recombinant Rhesus Macaque SYP Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
SYP-513HF Recombinant Full Length Human SYP Protein In Vitro Cell Free System Human Full L. 313 amino acids
SYP-5533R Recombinant Rat SYP Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
SYP-5533R-B Recombinant Rat SYP Protein Pre-coupled Magnetic Beads HEK293 Rat
SYP-6387H Recombinant Human SYP Protein (Glu50-Met313), N-His tagged E.coli Human His Glu50-Met313

    Involved Pathway

    SYP involved in several pathways and played different roles in them. We selected most pathways SYP participated on our site, such as Synaptic Vesicle Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SYP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Synaptic Vesicle Pathway SYN1,CPLX2,SYN3,PARK7,SYN2,STX1B,DNM1L

    Protein Function

    SYP has several biochemical functions, for example, SH2 domain binding,cholesterol binding,identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SYP itself. We selected most functions SYP had, and list some proteins which have the same functions with SYP. You can find most of the proteins on our site.

    Function Related Protein
    SH2 domain binding SYNGR3,CTR9,DAG1,SRC,PTK2,LILRB1,SKAP1,SH3PXD2B,INPPL1,JAK2
    identical protein binding AIM2,JMJD6,KHDC1A,PRKAB2,UAP1,CLDN7,TTN,AGXT2L2,ATF3,DYNLT1F
    cholesterol binding PMP2,APOEA,SOAT1,OSBP2,APOD,NPC1,STARD6,NPC2,PROM2,APOC3
    protein self-association L1CAM,DVL2,PROSAPIP1,ZFP639,TRIM32,ZSWIM2,CBR2,SLC2A1,PCSK9,S100A7A
    transporter activity SLC13A1,Abcb1b,AQP10B,OSTB,MIP,AQP12B,SLC22A17,TAP2,RBP2B,SLC23A3

    Interacting Protein

    SYP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SYP here. Most of them are supplied by our site. Hope this information will be useful for your research of SYP.

    HTT

    Resources

    References

    • Yang, JR; Liao, CH; et al. Transplantation of porcine embryonic stem cells and their derived neuronal progenitors in a spinal cord injury rat model. CYTOTHERAPY 15:201-208(2013).
    • Santos, LD; Torres, RM; et al. In-house ELISA method to analyze anti-Trypanosoma cruzi IgG reactivity for differential diagnosis and evaluation of Chagas disease morbidity. REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL 45:35-44(2012).

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