SYN2
-
Official Full Name
synapsin II -
Overview
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. The TIMP4 gene is located within an intron of this gene and is transcribed in the opposite direction. Mutations in this gene may be associated with abnormal presynaptic function and schizophrenia. Alternative splicing of this gene results in two transcripts. -
Synonyms
SYN2;synapsin II;synapsin-2;SYNII;SYNIIa;SYNIIb;SYN 2;SYN II;SYN IIa;SYN IIb;Synapsin 2;Synapsin II isoform IIa;Synapsin II isoform IIb;Synapsin2;SynapsinII
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- His
- Non
- His&T7
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SYN2-3071H | Recombinant Human SYN2, His-tagged | E.coli | Human | His | 233-582aa | |
| SYN2-16303M | Recombinant Mouse SYN2 Protein | Mammalian Cell | Mouse | His |
|
|
| SYN2-31489TH | Recombinant Human SYN2 | Wheat Germ | Human | Non | 101 amino acids |
|
| SYN2-5861R | Recombinant Rat SYN2 Protein | Mammalian Cell | Rat | His |
|
|
| Syn2-7890M | Recombinant Mouse Syn2 protein, His & T7-tagged | E.coli | Mouse | His&T7 | Leu88~Thr422 |
|
| Syn2-4332R | Recombinant Rat Syn2 protein, His-tagged | E.coli | Rat | His | 233-582aa |
|
| Syn2-4344R | Recombinant Rat Syn2 protein, His-tagged | E.coli | Rat | His | 88-422aa |
|
| SYN2-5520R | Recombinant Rat SYN2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
|
|
| SYN2-5520R-B | Recombinant Rat SYN2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
|
||
| SYN2-8909M | Recombinant Mouse SYN2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| SYN2-8909M-B | Recombinant Mouse SYN2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
Involved Pathway
SYN2 involved in several pathways and played different roles in them. We selected most pathways SYN2 participated on our site, such as Dopamine Neurotransmitter Release Cycle,Neuronal System,Neurotransmitter Release Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with SYN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Serotonin Neurotransmitter Release Cycle | PPFIA1,SYN3,RERG,SYN1,PPFIA2,PPFIA4,CPLX1 |
| Synaptic Vesicle Pathway | CPLX2,SYN1,DNM1L,STX1B,SYN3,SYP,PARK7 |
| Neuronal System | KCNH6,UNC13B,KCND1,KCNH2,KCNV1,KCNK10B,KCNH6A,KCNH5,PPFIA2,SYT1A |
| Neurotransmitter Release Cycle | PPFIA4,SNAP25B,SLC6A1A,SLC17A7A,RAB3AB,PPFIA1,LIN7C,CPLX2L,ARL6IP5A,RERG |
| Dopamine Neurotransmitter Release Cycle | SYN3,CPLX1,Apba1,UNC13B,PPFIA1,SYN1,CCDC167,LIN7C,LIN7A,RERG |
| Transmission across Chemical Synapses | PPFIA4,SLC17A7A,PPFIA1,CPLX2L,HAND2,SLC1A3B,LIN7C,Apba1,CACFD1,RERG |
Protein Function
SYN2 has several biochemical functions, for example, ATP binding,catalytic activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SYN2 itself. We selected most functions SYN2 had, and list some proteins which have the same functions with SYN2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| catalytic activity | PGAM1,RDH7,CWF19L2,FH1,LANCL1,SLC3A2,PCYT1AB,SPTLC2A,PPM1LA,DDAH2 |
| ATP binding | ACSM4,ABCA1,EIF4A1B,RPS6KB1B,MYO6,STRC,ADCK2,VRK3,ABCD4,DSTYK |
Interacting Protein
SYN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SYN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SYN2.
IQCB1
Resources
Related Services
Related Products
References
- Nagai, R; Hashimoto, R; et al. Drosophila Syntrophins are involved in locomotion and regulation of synaptic morphology. EXPERIMENTAL CELL RESEARCH 316:2313-2321(2010).
- Halden, Y; Rek, A; et al. Interleukin-8 binds to syndecan-2 on human endothelial cells. BIOCHEMICAL JOURNAL 377:533-538(2004).
