SV2C

  • Official Full Name

    synaptic vesicle glycoprotein 2C
  • Overview

    SV2s (Synaptic Vesicle protein 2) are integral membrane glycoproteins present in all synaptic vesicles. They have 12 transmembrane domains predicted by sequence analysis. There are three characterized isoforms, SV2A, SV2B and SV2C. SV2A is expressed ubiquitously throughout the brain. SV2B has a more restricted distribution with varying degrees of coexpression with SV2A. SV2C is more closely related to SV2A but shows a very restricted expression pattern; the highest expression levels being observed in phylogenetically old brain areas like pallidum, the midbrain and the olfactory bulb.
  • Synonyms

    SV2C;synaptic vesicle glycoprotein 2C;synaptic vesicle protein 2C

Recombinant Proteins

  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E. coli
  • Mammalian Cell
  • HEK293
  • His
  • His&Fc&Avi
  • GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
SV2C-2628H Recombinant Human SV2C protein, His-tagged E. coli Human His 450-524 aa
SV2C-16268M Recombinant Mouse SV2C Protein Mammalian Cell Mouse His
SV2C-5848R Recombinant Rat SV2C Protein Mammalian Cell Rat His
SV2C-6852Z Recombinant Zebrafish SV2C Mammalian Cell Zebrafish His
SV2C-5507R Recombinant Rat SV2C Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
SV2C-5507R-B Recombinant Rat SV2C Protein Pre-coupled Magnetic Beads HEK293 Rat
SV2C-6813H Recombinant Human SV2C protein, GST-tagged E. coli Human GST 91-140 aa
SV2C-6814H Recombinant Human SV2C protein, His-tagged E. coli Human His 91-140 aa
SV2C-6833H Recombinant Human SV2C protein, GST-tagged E. coli Human GST 450-524 aa
SV2C-8893M Recombinant Mouse SV2C Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
SV2C-8893M-B Recombinant Mouse SV2C Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    SV2C involved in several pathways and played different roles in them. We selected most pathways SV2C participated on our site, such as ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with SV2C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ECM-receptor interaction LAMA2,ITGB7,COL5A2A,IBSP,THBS3,VTN,ITGA6B,LAMC2,LAMB3,ITGB1

    Protein Function

    SV2C has several biochemical functions, for example, transmembrane transporter activity,transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SV2C itself. We selected most functions SV2C had, and list some proteins which have the same functions with SV2C. You can find most of the proteins on our site.

    Function Related Protein
    transmembrane transporter activity SLC2A1A,RALBP1,SLC2A13B,ATP5L,SLC2A3A,SLC17A9B,SLC2A9L1,SLC2A15A,SLC2A15B,ATP5H
    transporter activity AP2S1,SLC37A4B,RBP2,SYPL1,SLC4A2A,SYN1,GABRA5,ABCC6,ATP5D,AP3D1

    Interacting Protein

    SV2C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SV2C here. Most of them are supplied by our site. Hope this information will be useful for your research of SV2C.

    Resources

    Research Area

    Synaptic SNAREs

    References

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