SULT1C2
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Official Full Name
sulfotransferase family, cytosolic, 1C, member 2 -
Overview
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. -
Synonyms
SULT1C2;sulfotransferase family, cytosolic, 1C, member 2;sulfotransferase family, cytosolic, 1C, member 1 , SULT1C1;sulfotransferase 1C2;ST1C1;humSULTC2;ST1C2;ST1C2_HUMAN;Sulfotransferase 1C1;Sulfotransferase family cytosolic 1C member 1;Sulfotransferase family cytosolic 1C member 2;SULT1C#1;SULT1C1;OTTHUMP00000161571;OTTHUMP00000161572;OTTHUMP00000203304;OTTHUMP00000203390;OTTHUMP00000203867;sulfotransferase family, cytosolic, 1C, member 1
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Mammalian Cell
- HEK293
- E. coli
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
SULT1C2 involved in several pathways and played different roles in them. We selected most pathways SULT1C2 participated on our site, such as Biological oxidations,Cytosolic sulfonation of small molecules,Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with SULT1C2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Phase II conjugation | SULT1C4,UGT1B7,SULT1B1,UGT1B2,SULT1ST5,SULT1ST6,ABHD14B,AS3MT,UGT1B1,Sult2a6 |
| Sulfation Biotransformation Reaction | SULT1C4,SULT1B1,SULT4A1 |
| Biological oxidations | CYP2F1,GLYATL2,SULT1ST5,CYP3A5,COMT,CYP2AD3,NAT2,CYP2J2,NCOA2,CYP17A1 |
| Metabolism | IDO2,SACM1LA,PLD6,INSIG2,GLTPD1,CYP27A1,FAAH2A,BSG,COX11,SUMF2 |
| metapathway biotransformation | CYP20A1,NAT8,KCNAB1,KCNAB2,NAT14,SULT6B1,SULT4A1,CYP4Z1,NAA50,NAT8B |
| Cytosolic sulfonation of small molecules | Sult2a2,SULT4A1,SLC26A1,SULT1ST5,SLC35B2,SULT1B1,ABHD14B,SULT1C4,SULT2ST2,SULT2ST1 |
Protein Function
SULT1C2 has several biochemical functions, for example, protein binding,sulfotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SULT1C2 itself. We selected most functions SULT1C2 had, and list some proteins which have the same functions with SULT1C2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MEX3C,HNRNPU,APPB,TMED10,MANBAL,POC1A,MITD1,BECN1,SHOX,MLF2 |
| sulfotransferase activity | Sult3a1,SULT4A1,SULT2ST1,SULT1B1,Chst5,HS3ST3A1,SULT2ST3,Sult2a2,CHST12A,SULT1ST1 |
Interacting Protein
SULT1C2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SULT1C2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SULT1C2.
TINF2;TERF1;HLTF;RASGRP3;ACD;POT1
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