STX8
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Official Full Name
syntaxin 8 -
Overview
The gene is a member of the syntaxin family. The encoded protein is involved in protein trafficking from early to late endosomes via vesicle fusion and exocytosis. A related pseudogene has been identified on chromosome 12. Alternative splicing results in multiple transcript variants. -
Synonyms
STX8;syntaxin 8;syntaxin-8;CARB;STX 8;Syntaxin8;CIP-1-associated regulator of cyclin B
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Chicken
- Rhesus macaque
- Rat
- Mus musculus
- E.coli
- Mammalian Cell
- Human Cell
- E.coli expression system
- HEK293
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
STX8 involved in several pathways and played different roles in them. We selected most pathways STX8 participated on our site, such as SNARE interactions in vesicular transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with STX8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| SNARE interactions in vesicular transport | STX16,STX11B.1,BET1L,STX5,STX7,SEC22B,SNAP23.2,VAMP2,STX3,STX2 |
Protein Function
STX8 has several biochemical functions, for example, chloride channel inhibitor activity,protein binding,syntaxin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STX8 itself. We selected most functions STX8 had, and list some proteins which have the same functions with STX8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| syntaxin binding | SYT5,STX10,SYT1B,SYT1A,SYTL3,DOC2D,SNAP23.2,SYT11,CPLX4A,CPLX4B |
| chloride channel inhibitor activity | STX7,VTI1B,STX1A,WNK1,VAMP8,CFTR |
| ubiquitin protein ligase binding | FBXW7,BLZF1,RAD18,PRKAR2A,CUL5A,PTPN22,BID,TRIB3,POLR2A,TRIOBP |
| protein binding | HEBP2,EIF4EBP2,EMG1,SRPK3,AHCYL1,CD200,PACSIN3,SMARCD3,SMOC1,NUP50 |
Interacting Protein
STX8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STX8 here. Most of them are supplied by our site. Hope this information will be useful for your research of STX8.
STX4;CREB3;VTI1B;NSF;WDR91;GAMMAHV.ORF30;GAMMAHV.ORF35;carB;prfB;rbsK;q81x37_bacan;q99ib8-pro_0000045598;Sec24c;VAMP4;ATP6V1A;VAMP7
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