STEAP3
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Official Full Name
STEAP family member 3, metalloreductase -
Synonyms
STEAP3;STEAP family member 3, metalloreductase;24592;ENSG00000115107;STMP3;TSAP6;dudlin-2;2q14.2;metalloreductase STEAP3;metalloreductase STEAP3;pHyde;hTSAP6;hpHyde;dudlin 2;dudulin 2;dudulin-2;1010001D01Rik;tumor suppressor pHyde;six transmembrane prostate protein 3;tumor suppressor-activated pathway protein 6;six-transmembrane epithelial antigen of prostate 3
Recombinant Proteins
- Human
- Mouse
- Rat
- Mus musculus
- E.coli
- Mammalian Cells
- HEK293
- His
- Myc&DDK
- GST
- Flag
- His&Fc&Avi
Involved Pathway
STEAP3 involved in several pathways and played different roles in them. We selected most pathways STEAP3 participated on our site, such as p signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with STEAP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| p signaling pathway | CCNG1,RRM2B,PPM1DB,Casp3,CYCS,TP53AIP1,CCNB3,IGF1,TSC2,SIAH1A |
Protein Function
STEAP3 has several biochemical functions, for example, cupric reductase activity,ferric-chelate reductase (NADPH) activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STEAP3 itself. We selected most functions STEAP3 had, and list some proteins which have the same functions with STEAP3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | KRT17,IL1RL1,LRRFIP2,TMEM139,SETX,NUDT21,TMEM147,MXD3,PPARGC1A,KIAA0649 |
| ferric-chelate reductase (NADPH) activity | STEAP4,STEAP2 |
| metal ion binding | NUDT12,ITGAX,CYP46A1.4,ZDHHC3B,ZFP276,ZNF202,DNAJA3,ZNF446,SMPD3,FTR82 |
| cupric reductase activity | STEAP4,STEAP2 |
Interacting Protein
STEAP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STEAP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of STEAP3.
SETD7;BAD;pi3p
Resources
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References
- Blanc, L; Papoin, J; et al. Abnormal erythroid maturation leads to microcytic anemia in the TSAP6/Steap3 null mouse model. AMERICAN JOURNAL OF HEMATOLOGY 90:235-241(2015).
- Blanc, L; Papoin, J; et al. Ineffective Erythropoiesis Is the Major Cause of Microcytic Anemia in the TSAP6/Steap3 Null Mouse Model. BLOOD 124:-(2014).
