ST8SIA4
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Official Full Name
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -
Overview
The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
ST8SIA4;ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4;sialyltransferase 8 (alpha 2, 8 polysialytransferase) D , SIAT8D;CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase;PST;PST1;ST8Sia IV;Alpha 2 8 sialyltransferase 8D;CMP N acetylneuraminate poly alpha 2 8 sialyl transferase;Polysialyltransferase 1;Sialyltransferase 8 alpha 28 polysialytransferase D;SIAT8D;ST8 alpha N acetyl neuraminide alpha 2 8 sialyltransferase 4;ST8SIAIV;SIAT8-D;OTTHUMP00000158915;OTTHUMP00000227000;sialyltransferase 8D;polysialyltransferase-1;sialytransferase St8Sia IV;alpha-2,8-sialyltransferase 8D;sialyltransferase 8 (alpha-2, 8-polysialytransferase) D;CMP-N-acetylneuraminate-poly-alpha-2,8-sialyl transferase;ST8SIA-IV
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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| ST8SIA4-4504R | Recombinant Rhesus monkey ST8SIA4 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| ST8SIA4-5762Z | Recombinant Zebrafish ST8SIA4 | Mammalian Cell | Zebrafish | His |
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| ST8SIA4-5856C | Recombinant Chicken ST8SIA4 | Mammalian Cell | Chicken | His |
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| ST8SIA4-1067H | Recombinant Human ST8SIA4 Protein (21-168 aa), His-SUMO-tagged | E.coli | Human | His&SUMO | 21-168 aa |
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| ST8SIA4-4320R | Recombinant Rhesus Macaque ST8SIA4 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| ST8SIA4-4320R-B | Recombinant Rhesus Macaque ST8SIA4 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
ST8SIA4 involved in several pathways and played different roles in them. We selected most pathways ST8SIA4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ST8SIA4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
ST8SIA4 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ST8SIA4 itself. We selected most functions ST8SIA4 had, and list some proteins which have the same functions with ST8SIA4. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
ST8SIA4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ST8SIA4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ST8SIA4.
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References
- Davis, NA; Lareau, CA; et al. Encore: Genetic Association Interaction Network Centrality Pipeline and Application to SLE Exome Data. GENETIC EPIDEMIOLOGY 37:614-621(2013).
