ST6GALNAC2
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Official Full Name
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -
Overview
ST6GALNAC2 belongs to a family of sialyltransferases that add sialic acids to the nonreducing ends of glycoconjugates.;At the cell surface, these modifications have roles in cell-cell and cell-substrate interactions, bacterial adhesion,;and protein targeting (Samyn-Petit et al., 2000 (PubMed 10742600)). -
Synonyms
ST6GALNAC2;ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2;sialyltransferase 7 ((alpha N acetylneuraminyl 2,3 beta galactosyl 1,3) N acetyl galactosaminide alpha 2,6 sialyltransferase) , sialyltransferase like 1 , SIAT7, SIAT7B, SIATL1;alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2;ST6GalNAII;STHM;SAITL1;(alpha N acetylneuraminyl 2 3 beta galactosyl 1 3) N acetyl galactosaminide alpha 2 6 sialyltransferase;(alpha N acetylneuraminyl 2 3 beta galactosyl 1 3) N acetyl galactosaminide B;Alpha N acetylgalactosaminide alpha 2 6 sialyltransferase 2;FLJ45660;GalNAc alpha 2 6 sialyltransferase II;Sialyltransferase 7;Sialyltransferase 7B;Sialyltransferase like 1;Sialyltransferase7;SIAT7;SIAT7B;SIATL1;ST6 (alpha N acetyl neuraminyl 2 3 beta galactosyl 1 3) N acetylgalactosaminide alpha 2 6 sialyltransferase 2;ST6GalNAc II;SIAT7-B;ST6GalNAcII;sialyltransferase-like 1;galNAc alpha-2,6-sialyltransferase II;(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide B;sialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide B;(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase;sialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) B
Recombinant Proteins
- Human
- Mouse
- Chicken
- Zebrafish
- Mus musculus
- E.coli
- HEK293
- E.Coli or Yeast
- Mammalian Cell
- Human Cell
- E.coli expression system
- Mammalian cells
- His
- Non
- His&GFP
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ST6GALNAC2-2979H | Recombinant Human ST6GALNAC2, His-tagged | E.coli | Human | His | 38-374aa | |
| ST6GALNAC2-195H | Recombinant Human ST6GALNAC2, His-tagged | HEK293 | Human | His | 1-374 a.a. |
|
| St6galnac2-3379M | Recombinant Mouse St6galnac2, His-tagged | E.Coli or Yeast | Mouse | His | 373 |
|
| ST6GALNAC2-6786C | Recombinant Chicken ST6GALNAC2 | Mammalian Cell | Chicken | His |
|
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| ST6GALNAC2-7662Z | Recombinant Zebrafish ST6GALNAC2 | Mammalian Cell | Zebrafish | His |
|
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| ST6GALNAC2-912M | Recombinant Mouse ST6GALNAC2 Protein, His-tagged | HEK293 | Mouse | His | 28-373 a.a. |
|
| ST6GALNAC2-1613MCL | Recombinant Mouse ST6GALNAC2 cell lysate | Human Cell | Mouse | Non |
|
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| RFL6619MF | Recombinant Full Length Mouse Alpha-N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 2(St6Galnac2) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length (1-373) |
|
| ST6GALNAC2-16H | Active Recombinant Human ST6GALNAC2 Protein (AA 68-374), N-6×His/GFP tagged | HEK293 | Human | His&GFP | AA 68-374 |
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| ST6GALNAC2-5563H | Recombinant Human ST6GALNAC2 Protein (Ser29-Arg374), C-His tagged | Mammalian cells | Human | His | Ser29-Arg374 |
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Involved Pathway
ST6GALNAC2 involved in several pathways and played different roles in them. We selected most pathways ST6GALNAC2 participated on our site, such as Asparagine N-linked glycosylation,Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein,Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with ST6GALNAC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| O-linked glycosylation | THSD7A,MUC4,MUC15,ADAMTS10,ADAMTSL4,MUC5AC,KCNA6,GALNT5,B3GNT2A,MUC21 |
| Asparagine N-linked glycosylation | LMAN2L,SEC16B,TRAPPC3,CSNK1D,CTAGE5,CNIH,ST8SIA2,CNIH3,TRAPPC4,NAPAA |
| O-linked glycosylation of mucins | MUC1,B3GNT6,GALNT5,MUCL1,MUC20,GALNTL5,GCNT3,B3GNT8,GALNT13,MUC21 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | MPDU1B,DPAGT1,MPDU1A,NANP,SLC35A1,ALG14,ST6GAL2B,ST8SIA2,MPDU1,ALG10B |
| Post-translational protein modification | YKT6,MUC15,MLEC,ARSD,RING1,CBX8,EIF5A,SPON1,SCMH1,LMAN2L |
| Metabolism of proteins | SPON1,TBCD,CTAGE5,TTR,INHA,SEMG1,ST6GALNAC1.2,FURINB,NEU4,SERPINA7 |
| Sialic acid metabolism | NANP,ST8SIA3,ST6GAL2B,SLC35A1,ST6GALNAC1.2,GNE |
| Synthesis of substrates in N-glycan biosythesis | ST6GAL2B,ST6GALNAC1.2,SLC35A1,ST8SIA3,GNE |
Protein Function
ST6GALNAC2 has several biochemical functions, for example, sialyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ST6GALNAC2 itself. We selected most functions ST6GALNAC2 had, and list some proteins which have the same functions with ST6GALNAC2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sialyltransferase activity | ST6GAL2B,ST6GALNAC1.2,ST6GALNAC5,ST6GALNAC6,ST6GAL1,ST6GALNAC3,ST8SIA3,ST3GAL3B,ST6GALNAC1,ST3GAL3A |
Interacting Protein
ST6GALNAC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ST6GALNAC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ST6GALNAC2.
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References
- Kroes, RA; He, HA; et al. Overexpression of ST6GalNAcV, a ganglioside-specific alpha 2,6-sialyltransferase, inhibits glioma growth in vivo. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 107:12646-12651(2010).
