SSU72
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Official Full Name
SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) -
Overview
May be involved in the C-terminal domain of RNA polymerase II dephosphorylation, RNA processing and termination. -
Synonyms
SSU72;SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae);Ssu72 RNA polymerase II CTD phosphatase homolog (yeast);RNA polymerase II subunit A C-terminal domain phosphatase SSU72;HSPC182;Hypothetical protein FLJ10947;Ssu72 RNA polymerase II CTD phosphatase homolog;CTD phosphatase SSU72;PNAS-120
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Chicken
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
SSU72 involved in several pathways and played different roles in them. We selected most pathways SSU72 participated on our site, such as mRNA surveillance pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SSU72 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| mRNA surveillance pathway | PABPC5,PPP1CAA,SMG6,PPP2R2C,UPF3A,SRRM1,FIP1L1,FIP1L1B,PPP2R5A,CPSF1 |
Protein Function
SSU72 has several biochemical functions, for example, CTD phosphatase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SSU72 itself. We selected most functions SSU72 had, and list some proteins which have the same functions with SSU72. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | IFT20,SIGIRR,COMP,ARHGEF16,NRCAM,ZNF114,TUBGCP4,MSTN,CALM2,TUBA3C |
| CTD phosphatase activity | CTDSP1,RPAP2,PPM1M,CTDSPLB,CTDSPLA,CTDSP2,CTDSPL,CTDP1 |
Interacting Protein
SSU72 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SSU72 here. Most of them are supplied by our site. Hope this information will be useful for your research of SSU72.
RAD21;STAG2;UIMC1;MAPK8;MAPK9;SMC1A;SMC3
Resources
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References
- Allepuz-Fuster, P; Martinez-Fernandez, V; et al. Rpb4/7 facilitates RNA polymerase II CTD dephosphorylation. NUCLEIC ACIDS RESEARCH 42:13674-13688(2014).
- Rosado-Lugo, JD; Hampsey, M; et al. The Ssu72 Phosphatase Mediates the RNA Polymerase II Initiation-Elongation Transition. JOURNAL OF BIOLOGICAL CHEMISTRY 289:33916-33926(2014).
