SSPN
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Official Full Name
sarcospan (Kras oncogene-associated gene) -
Overview
This gene encodes a member of the dystrophin-glycoprotein complex (DGC). The DGC spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Two alternatively spliced transcript variants that encode different protein isoforms have been described. -
Synonyms
SSPN;sarcospan (Kras oncogene-associated gene);KRAG;sarcospan;SPN1;SPN2;K ras oncogene associated gene;K ras oncogene associated protein;Kirsten ras associated protein;microspan;Kirsten-ras associated;kirsten-ras-associated protein;K-ras oncogene-associated protein;NSPN;DAGA5;nanospan
Recombinant Proteins
- Bacillus subtilis
- Zebrafish
- Rhesus macaque
- Human
- Mus musculus
- Oryctolagus cuniculus (Rabbit)
- Mouse
- E. coli or Yeast
- Mammalian Cell
- E.coli expression system
- HEK293T
- HEK293
- E.coli
- Mammalian cells
- His
- Non
- Myc&DDK
- His&Fc&Avi
- GST
- Flag
Involved Pathway
SSPN involved in several pathways and played different roles in them. We selected most pathways SSPN participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SSPN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SSPN has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SSPN itself. We selected most functions SSPN had, and list some proteins which have the same functions with SSPN. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
SSPN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SSPN here. Most of them are supplied by our site. Hope this information will be useful for your research of SSPN.
Resources
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References
- Wakayama, Y; Inoue, M; et al. Reduced expression of sarcospan in muscles of Fukuyama congenital muscular dystrophy. HISTOLOGY AND HISTOPATHOLOGY 23:1425-1438(2008).
- Hayashi, K; Wakayama, Y; et al. Sarcospan: Ultrastructural localization and its relation to the sarcoglycan subcomplex. MICRON 37:591-596(2006).
