SRSF3

  • Official Full Name

    serine/arginine-rich splicing factor 3

  • Overview

    The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants, one protein-coding and the other non-coding, have been found for this gene.

  • Synonyms

    SFRS3;SRp20;serine/arginine-rich splicing factor 3;OTTHUMP00000016294;pre-mRNA-splicing factor SRP20;splicing factor, arginine/serine-rich 3;splicing factor, arginine/serine-rich, 20-kD
Cat.# Product name Source (Host) Species Tag Protein Length Price
SRSF3-26854TH Recombinant Human SRSF3 Wheat Germ Human Non 164 amino acids
SRSF3-26855TH Recombinant Human SRSF3 Wheat Germ Human Non 85 amino acids
SRSF3-4142C Recombinant Chicken SRSF3 Mammalian Cell Chicken His
SRSF3-1904HCL Recombinant Human SFRS3 293 Cell Lysate HEK293 Human Non
SRSF3-4573H Recombinant Human SRSF3 protein, His-GB1-tagged E.coli Human His&GB1 1-86aa
SRSF3-497HF Recombinant Full Length Human SRSF3 Protein In Vitro Cell Free System Human Full L. 164 amino acids

    Involved Pathway

    SRSF3 involved in several pathways and played different roles in them. We selected most pathways SRSF3 participated on our site, such as Spliceosome,Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with SRSF3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Spliceosome SF3B14,DHX15,DHX8,SNRPF,AQR,U2AF1,SRSF5A,TCERG1A,SNRPA,SFRS9
    Herpes simplex infection IRF7,HLA-DRB4,SRSF2B,Ccl12,C1QBP,Fasl,ARNTL,SRSF2A,CYCS,BLA

    Protein Function

    SRSF3 has several biochemical functions, for example, RNA binding,nucleotide binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SRSF3 itself. We selected most functions SRSF3 had, and list some proteins which have the same functions with SRSF3. You can find most of the proteins on our site.

    Function Related Protein
    RNA binding JMJD6,BARD1,SETD1BA,KHDC1,CELF3,MIF4GD,EIF2S1A,DUSP11,RPL13,EIF5A
    nucleotide binding MYO6B,RBM4.2,NONO,GNAO1B,EWSR1A,CLK2A,CKMT2B,ABCD3,APOA1BP,PCXB
    protein binding TGFBR3,MAPK1,PFN2,FAM109A,FAM113A,NTS,CNOT2,ESRRG,ITSN1,JAGN1
    poly(A) RNA binding MECP2,CIRBP,HSD17B10,FAM50A,EBI3,MRPL15,SUPT6H,CEBPZ,RPS4Y1,PDAP1

    Interacting Protein

    SRSF3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SRSF3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SRSF3.

    PCBP2;NXF1;Dazl;Srek1;EIF4A3;MAGOH;SRPK2;SRPK1;YWHAQ;YWHAB

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