SRPK3
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Official Full Name
SRSF protein kinase 3 -
Overview
This gene encodes a protein kinase similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors. A highly similar protein has been shown to play a role in muscle development in mice. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
SRPK3;SRSF protein kinase 3;serine/threonine kinase 23 , SFRS protein kinase 3 , STK23;MSSK1;SFRS protein kinase 3;serine/threonine kinase 23;SR-protein-specific kinase 3;muscle-specific serine kinase 1;serine/threonine-protein kinase 23;serine/
Recombinant Proteins
- Human
- Mouse
- Insect Cells
- Mammalian cells
- Sf9 Insect Cell
- Insect Cell
- E.coli
- HEK293
- HEK293T
- His&GST
- Flag
- Non
- GST
- His&T7
- His&Fc&Avi
- Myc&DDK
Involved Pathway
SRPK3 involved in several pathways and played different roles in them. We selected most pathways SRPK3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SRPK3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SRPK3 has several biochemical functions, for example, ATP binding,protein binding,protein serine/threonine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SRPK3 itself. We selected most functions SRPK3 had, and list some proteins which have the same functions with SRPK3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CCL18,ZC3H15,SEPT11,RAP1GAP,DYNLT1,PPP1R16B,LPL,KIF9,SHKBP1,ELMO3 |
| protein serine/threonine kinase activity | GAK,SGK2B,TESK2,AKT3A,DYRK2,SRPK1,AURKA,ACVR1BA,CAMK2B1,MARK3 |
| ATP binding | FARSA,MYH1E,DDX39A,HSPE1,MYO6A,ABL2,ATP1A1,LATS2,SMC6,DNAJA3A |
Interacting Protein
SRPK3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SRPK3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SRPK3.
SRPK1;HSP90AB1;NOP56;DHX15;HNRNPR;PRKRA;RSL1D1;STAU1;SNRNP70;SNRPA;SNRPC;SNRPB;YBX3;SON;NCL;RBMX;RBM34;NOP2;HNRNPM
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References
- Iwasa, M; Yamagata, T; et al. Contiguous ABCD1 DXS1357E deletion syndrome: Report of an autopsy case. NEUROPATHOLOGY 33:292-298(2013).
- Zhang, ML; Zhu, B; et al. Alternative Splicing of MEF2C pre-mRNA Controls Its Activity in Normal Myogenesis and Promotes Tumorigenicity in Rhabdomyosarcoma Cells. JOURNAL OF BIOLOGICAL CHEMISTRY 290:310-324(2015).
