SPIRE2
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Official Full Name
spire homolog 2 (Drosophila) -
Synonyms
SPIRE2;spire homolog 2 (Drosophila);protein spire homolog 2;KIAA1832;spir 2;MGC117166;Spir-2;SPIR2_HUMAN
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SPIRE2-2923H | Recombinant Human SPIRE2, His-tagged | E.coli | Human | His | 318-666aa |
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| SPIRE2-15903M | Recombinant Mouse SPIRE2 Protein | Mammalian Cell | Mouse | His |
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| SPIRE2-1731Z | Recombinant Zebrafish SPIRE2 | Mammalian Cell | Zebrafish | His |
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| SPIRE2-1506HCL | Recombinant Human SPIRE2 293 Cell Lysate | HEK293 | Human | Non |
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| SPIRE2-4646H | Recombinant Human SPIRE2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Spire2-6101M | Recombinant Mouse Spire2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| SPIRE2-8661M | Recombinant Mouse SPIRE2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SPIRE2-8661M-B | Recombinant Mouse SPIRE2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SPIRE2 involved in several pathways and played different roles in them. We selected most pathways SPIRE2 participated on our site, such as Dorso-ventral axis formation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SPIRE2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Dorso-ventral axis formation | NOTCH4,SOS1,PIWIL4,NOTCH1A,MAPK1,NOTCH1B,GRB2B,GRB2,PPP1R2P9,NOTCH2 |
Protein Function
SPIRE2 has several biochemical functions, for example, actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SPIRE2 itself. We selected most functions SPIRE2 had, and list some proteins which have the same functions with SPIRE2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin binding | KLHL33,Fert2,FSCN1A,AFAP1,EMD,INPPL1B,ABLIM2,PXK,WAS,MYO19 |
Interacting Protein
SPIRE2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPIRE2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SPIRE2.
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References
- Pechlivanis, M; Samol, A; et al. Identification of a Short Spir Interaction Sequence at the C-terminal End of Formin Subgroup Proteins. JOURNAL OF BIOLOGICAL CHEMISTRY 284:25324-25333(2009).
- Quinlan, ME; Hilgert, S; et al. Regulatory interactions between two actin nucleators, Spire and Cappuccino. JOURNAL OF CELL BIOLOGY 179:117-128(2007).
- Schumacher, N; Borawski, JM; et al. Overlapping expression pattern of the actin organizers Spir-1 and formin-2 in the developing mouse nervous system and the adult brain. GENE EXPRESSION PATTERNS 4:249-255(2004).
- CHEUNG, HK; SERANO, TL; et al. EVIDENCE FOR A HIGHLY SELECTIVE RNA TRANSPORT-SYSTEM AND ITS ROLE IN ESTABLISHING THE DORSOVENTRAL AXIS OF THE DROSOPHILA EGG. DEVELOPMENT 114:653-661(1992).
