SPAG16
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Official Full Name
sperm associated antigen 16 -
Overview
Cilia and flagella are comprised of a microtubular backbone, the axoneme, which is organized by the basal body and;surrounded by plasma membrane. SPAG16 encodes 2 major proteins that associate with the axoneme of sperm tail and the;nucleus of postmeiotic germ cells, respectively (Zhang et al., 2007 (PubMed 17699735)). -
Synonyms
SPAG16;sperm associated antigen 16;sperm-associated antigen 16 protein;DKFZp666P1710;FLJ22724;PF20;WDR29;WD repeat domain 29;pf20 protein homolog;sperm-associated WD repeat protein;FLJ37717;MGC87036
Recombinant Proteins
- Human
- Cynomolgus
- Mouse
- E.coli
- Mammalian Cell
- HEK293T
- HEK293
- His
- Myc&DDK
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SPAG16-2892H | Recombinant Human SPAG16, His-tagged | E.coli | Human | His | 1-181aa | |
| SPAG16-961C | Recombinant Cynomolgus SPAG16 Protein, His-tagged | Mammalian Cell | Cynomolgus | His |
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| SPAG16-1615H | Recombinant Human SPAG16 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| SPAG16-2510H | Recombinant Human SPAG16 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| SPAG16-4631H | Recombinant Human SPAG16 protein, GST-tagged | E.coli | Human | GST | 1-183aa |
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| Spag16-6069M | Recombinant Mouse Spag16 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| SPAG16-704C | Recombinant Cynomolgus Monkey SPAG16 Protein, His (Fc)-Avi-tagged | HEK293 | Cynomolgus | His&Fc&Avi |
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| SPAG16-704C-B | Recombinant Cynomolgus Monkey SPAG16 Protein Pre-coupled Magnetic Beads | HEK293 | Cynomolgus |
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| SPAG16-989H | Recombinant Human SPAG16 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
SPAG16 involved in several pathways and played different roles in them. We selected most pathways SPAG16 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SPAG16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SPAG16 has several biochemical functions, for example, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SPAG16 itself. We selected most functions SPAG16 had, and list some proteins which have the same functions with SPAG16. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein kinase binding | THY1,CCND2,CCNB1,POLA1,BCL2L1,DPYSL2,CDH2,HNRNPA0,EPHA1,CHRNA7 |
Interacting Protein
SPAG16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPAG16 here. Most of them are supplied by our site. Hope this information will be useful for your research of SPAG16.
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References
- Krabben, A; Huizinga, TWJ; et al. Biomarkers for Radiographic Progression in Rheumatoid Arthritis. CURRENT PHARMACEUTICAL DESIGN 21:147-169(2015).
- de Bock, L; Somers, K; et al. Sperm-Associated Antigen 16 Is a Novel Target of the Humoral Autoimmune Response in Multiple Sclerosis. JOURNAL OF IMMUNOLOGY 193:2147-2156(2014).
- Shi, Y; Zhang, L; et al. The mouse transcription factor-like 5 gene encodes a protein localized in the manchette and centriole of the elongating spermatid. ANDROLOGY 1:431-439(2013).
- Somers, V; Govarts, C; et al. Autoantibody profiling in multiple sclerosis reveals novel antigenic candidates. JOURNAL OF IMMUNOLOGY 180:3957-3963(2008).
