SOX8

  • Official Full Name

    SRY (sex determining region Y)-box 8

  • Overview

    This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).

  • Synonyms

    SOX8;SRY (sex determining region Y)-box 8;transcription factor SOX-8;MGC24837;SOX 8;SRY (sex determining region Y) box 8;SRY box 8;SRY box containing gene 8;Transcription factor SOX 8;Transcription factor SOX8;OTTHUMP00000151195

Recombinant Proteins

  • Human
  • Mouse
  • Chicken
  • E.coli
  • Mammalian Cell
  • HEK293T
  • HEK293
  • His
  • Non
  • Myc&DDK
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
SOX8-2885H Recombinant Human SOX8, His-tagged E.coli Human His C-149aa
SOX8-15787M Recombinant Mouse SOX8 Protein Mammalian Cell Mouse His
SOX8-6296C Recombinant Chicken SOX8 Mammalian Cell Chicken His
SOX8-1673M Sol8 (mouse myoblast) whole cell lysate Human Non
SOX8-1743H Recombinant Human SOX8 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
SOX8-2419H Recombinant Human SOX8 Protein, MYC/DDK-tagged HEK293 Human Myc&DDK
SOX8-2795H Recombinant Human SOX8 protein(121-230 aa), C-His-tagged E.coli Human His 121-230 aa
Sox8-6059M Recombinant Mouse Sox8 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
SOX8-8594M Recombinant Mouse SOX8 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
SOX8-8594M-B Recombinant Mouse SOX8 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    SOX8 involved in several pathways and played different roles in them. We selected most pathways SOX8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SOX8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    SOX8 has several biochemical functions, for example, DNA binding,RNA polymerase II core promoter sequence-specific DNA binding,RNA polymerase II transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SOX8 itself. We selected most functions SOX8 had, and list some proteins which have the same functions with SOX8. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase II core promoter sequence-specific DNA binding PAX8,SMAD1,TAL1,RREB1,FOS,SPI1,NLRC5,IRF7,TP53,SP3
    transcription factor binding INSIG2,SIX2,FOSB,HMGA1-RS1,HEY1,TAF1,ATOH8,NBN,HDAC3,KAT2B
    protein heterodimerization activity KCNA3,ERBB3,APITD1,TCF3,HIST1H47,TLR2,HIST1H2BM,UGT1A3,BCL2L10,H2-AB1
    RNA polymerase II transcription factor activity, sequence-specific DNA binding ARX,ATF5,MED1,ZNF174,SPIC,FLI1B,FOXA,EF1,ATF4B2,KLF11
    DNA binding MIER1B,HER13,LIN28B,PAX7A,SMARCC1B,SIM1A,ZMAT4,DRGX,MLF1,TFDP3

    Interacting Protein

    SOX8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SOX8 here. Most of them are supplied by our site. Hope this information will be useful for your research of SOX8.

    MMP1;JAM2;PIDD1;NOD1

    Resources

    References

    Reviews

    Write a review

    Q&As

    Ask a question

    Ask a Question for All SOX8 Products

    Required fields are marked with *

    My Review for All SOX8 Products

    Required fields are marked with *