SNRPE
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Official Full Name
small nuclear ribonucleoprotein polypeptide E -
Overview
SNRPE, also known as SME, aids in the cytoplasmic construction of the UsnRNPs by binding to a conserved Sm site on UsnRNA and forming a stable snRNP core complex. As a core protein to UsnRNP, the SNRPE associates with the entire U family of snRNAs includ -
Synonyms
SNRPE;small nuclear ribonucleoprotein polypeptide E;small nuclear ribonucleoprotein E;Sm E;snRNP-E;sm protein E;SME;Sm-E;B-raf
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rhesus macaque
- Chicken
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
SNRPE involved in several pathways and played different roles in them. We selected most pathways SNRPE participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNRPE were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Spliceosome | SF3B3,PPIL1,U2AF2B,TRA2A,SRSF7B,ISY1-RAB43,HSPA1B,SNRPA,HNRPK,PRPF40B |
Protein Function
SNRPE has several biochemical functions, for example, RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNRPE itself. We selected most functions SNRPE had, and list some proteins which have the same functions with SNRPE. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MCM3,STIM1,SPRR2E,CCL5,CCDC137,ANP32A,WDR24,INO80B,CLDN8,S100A10 |
| RNA binding | PRAC,TRNAU1APA,RBBP7,SRSF9,RBM4B,MARF1,JAKMIP1,PPIE,PCBP4,ZFP36L3 |
Interacting Protein
SNRPE has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNRPE here. Most of them are supplied by our site. Hope this information will be useful for your research of SNRPE.
SNRPF;SNRPG;GEMIN2;LSM2;CLNS1A;GEMIN5;STRAP
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References
- Lauber, J; Plessel, G; et al. The human U4/U6 snRNP contains 60 and 90kD proteins that are structurally homologous to the yeast splicing factors Prp4p and Prp3p. RNA-A PUBLICATION OF THE RNA SOCIETY 3:926-941(1997).
- Brahms, H; Raker, VA; et al. A major, novel systemic lupus erythematosus autoantibody class recognizes the E, F, and G Sm snRNP proteins as an E-F-G complex but not in their denatured states. ARTHRITIS AND RHEUMATISM 40:672-682(1997).
