SMARCD1
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Official Full Name
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 -
Overview
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
SMARCD1;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1;BAF60A;CRACD1;Rsc6p;Swp73-like protein;BRG1-asso
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SMARCD1-15604M | Recombinant Mouse SMARCD1 Protein | Mammalian Cell | Mouse | His |
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| SMARCD1-9819Z | Recombinant Zebrafish SMARCD1 | Mammalian Cell | Zebrafish | His |
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| SMARCD1-1668HCL | Recombinant Human SMARCD1 293 Cell Lysate | HEK293 | Human | Non |
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| SMARCD1-8466M | Recombinant Mouse SMARCD1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SMARCD1-8466M-B | Recombinant Mouse SMARCD1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SMARCD1 involved in several pathways and played different roles in them. We selected most pathways SMARCD1 participated on our site, such as Chromatin modifying enzymes,Chromatin organization,Glucocorticoid receptor regulatory network, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMARCD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Prostate Cancer | NKX3-1,FOXO1,MAP2K2,PDGFD,PDGFRB,HSP90B1,NDRG1,NOXA1,BRAF,SPINK1 |
| RMTs methylate histone arginines | PBRM1L,ACTL6B,SMARCB1B,SMARCD3,SMARCE1,SMARCC1,SMARCB1,SMARCA4,SMARCA2,PRMT6 |
| Glucocorticoid receptor regulatory network | SMARCA4,KRT17,SMARCC2,KRT14,KRT5,CSN2,EGR1,POU2F1,NR1I3,BGLAP |
| Chromatin modifying enzymes | EED,PRDM16,MTA1,KDM5BB,SETD3,SMYD2,SMARCD3B,YEATS4,MBD3B,MBD3A |
| Chromatin organization | GATAD2B,ARID2,SMARCE1,MBD3A,MEAF6,PHF8,DMAP1,SUDS3,MBIP,SMARCC1B |
Protein Function
SMARCD1 has several biochemical functions, for example, chromatin binding,protein binding,protein complex scaffold. Some of the functions are cooperated with other proteins, some of the functions could acted by SMARCD1 itself. We selected most functions SMARCD1 had, and list some proteins which have the same functions with SMARCD1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein complex scaffold | ISCU,AKAP9,TELO2,WWC2,WWC1,SEPT2,AXIN1,MAGI1,DISC1,WWC3 |
| protein binding | GPR19,GOLGA2,XCL2,FES,DYNC1I2,VMP1,FLII,SYT6,PAK1,PCP4 |
| transcription coactivator activity | BRCA1,PER2,TADA3,EDF1,E4F1,NR1I2,TFDP1A,MED17,ING4,RB1 |
| receptor binding | FIS1,PSPN,CXCL12,PLG,AKAP9,NSG1,CRH,RARRES2,EPHX2,GSTM7 |
| chromatin binding | CHAF1B,SAFB,SREBF1,JMJD5,TOX3,SP3,NR5A1A,URI1,UBTFL,LEF1 |
Interacting Protein
SMARCD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMARCD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMARCD1.
SMARCC1;SMARCA4;VPS37B;MED4;CALCOCO2
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