SLIT1
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Official Full Name
slit homolog 1 -
Overview
Slit homolog 1 protein is a protein that in humans is encoded by the SLIT1 gene. -
Synonyms
SLIT1;slit homolog 1 (Drosophila);SLIL1, slit (Drosophila) homolog 1;slit homolog 1 protein;MEGF4;Slit 1;SLIT3;multiple EGF-like domains protein 4;multiple epidermal growth factor-like domains protein 4;SLIL1;SLIT-1;MGC164811
Recombinant Proteins
- Human
- Mouse
- Chicken
- Rat
- CHO
- Mammalian Cell
- E.coli
- HEK293T
- HEK293
- His
- Myc&DDK
- His&Fc&Avi
Involved Pathway
SLIT1 involved in several pathways and played different roles in them. We selected most pathways SLIT1 participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLIT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Axon guidance | NRG4,PLXNA3,EFNA5,COL9A1B,EPHB1,CD24,ROBO3,CFL2,RHOD,RASGRP4 |
Protein Function
SLIT1 has several biochemical functions, for example, Roundabout binding,calcium ion binding,heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLIT1 itself. We selected most functions SLIT1 had, and list some proteins which have the same functions with SLIT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | KCNIP3,F9,EFCAB6,PRSS3,CALB2,VCANB,CCDC47,NOTCH4,MMP14B,CDH10A |
| heparin binding | FMODA,CECR1,FGFR1A,ADAMTS8,UBE4A,AAMP,NOV,CXCL11,GPNMB,RSPO2 |
| Roundabout binding | SLIT3,GM4980,UBE4A,SLIT1A,TGFB1I1,SLIT1B,SLIT2 |
Interacting Protein
SLIT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLIT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLIT1.
ATN1;q9wmx2-pro_0000037548
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References
- Gangaraju, S; Sultan, K; et al. Cerebral endothelial expression of Robo1 affects brain infiltration of polymorphonuclear neutrophils during mouse stroke recovery. NEUROBIOLOGY OF DISEASE 54:24-31(2013).
- Ghoshal, K; Motiwala, T; et al. HOxB13, a Target of DNMT3B䀤 Is Methylated at an Upstream CpG I3land, and ⁆ၵnctions as a Tumor ѓuppၲessor in Primary Colorectal Tumors. PLOSĠONE 4:-e10338(5).
- Kim, M; Fontelonga, T; et al. Motor neuron cell bodies are actively positioned by Slit/Robo repulsion and Netrin/DCC attraction. DEVELOPMENTAL BIOLOGY 399:68-79(2015).
- Knoll, B; Schmidt, H; et al. On the topographic targeting of basal vomeronasal axons through Slit-mediated chemorepulsion. DEVELOPMENT 130:5073-5082(2003).
