SLC2A2

  • Official Full Name

    solute carrier family 2 (facilitated glucose transporter), member 2

  • Overview

    Glucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine,;and kidney epithelium. It mediates facilitated bidirectional glucose transport. Because of its low affinity for;glucose, it has been suggested as a glucose sensor.

  • Synonyms

    SLC2A2;solute carrier family 2 (facilitated glucose transporter), member 2;GLUT2;solute carrier family 2, facilitated glucose transporter member 2;GLUT-2;glucose transporter type 2, liver

Recombinant Proteins

  • Human
  • Mouse
  • Zebrafish
  • Chicken
  • Sus scrofa (Pig)
  • E.coli
  • Mammalian Cell
  • Wheat Germ
  • E.coli expression system
  • Insect Cell
  • HEK293
  • GST
  • His
  • Non
  • His&Flag&MBP
  • His&GST
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
SLC2A2-2744H Recombinant Human SLC2A2, GST-tagged E.coli Human GST 242-301aa
SLC2A2-15363M Recombinant Mouse SLC2A2 Protein Mammalian Cell Mouse His
SLC2A2-28420TH Recombinant Human SLC2A2 Wheat Germ Human Non 67 amino acids
SLC2A2-3829Z Recombinant Zebrafish SLC2A2 Mammalian Cell Zebrafish His
SLC2A2-7118C Recombinant Chicken SLC2A2 Mammalian Cell Chicken His
RFL6763SF Recombinant Full Length Pig Solute Carrier Family 2, Facilitated Glucose Transporter Member 2(Slc2A2) Protein, His-Tagged E.coli expression system Sus scrofa (Pig) His Full L. Full Length (1-120)
SLC2A2-0480H Recombinant Human SLC2A2 Protein (T2-V524), 8×His-MBP, Flag tagged Insect Cell Human His&Flag&MBP T2-V524
SLC2A2-1781H Recombinant Human SLC2A2 protein, His & GST-tagged E.coli Human His&GST Cys239~Pro303
SLC2A2-8312M Recombinant Mouse SLC2A2 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
SLC2A2-8312M-B Recombinant Mouse SLC2A2 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    SLC2A2 involved in several pathways and played different roles in them. We selected most pathways SLC2A2 participated on our site, such as Insulin secretion,Prolactin signaling pathway,Type II diabetes mellitus, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC2A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Central carbon metabolism in cancer PGAM2,PIK3R5,PDHA1,TRP53,HK3,PDHA2,PDGFRA,MET,GLS2,IDH1
    Prolactin signaling pathway INS1,CSN2,MAPK13,SOCS1,HRAS,PIK3R3,STAT5B,MAPK9,MAPK8,ELF5
    Carbohydrate digestion and absorption AKT1,G6PC3,ATP1A1,AMY1B,GNAT3,PIK3CG,HK1,Amy1,PIK3CB,PIK3R3
    Maturity onset diabetes of the young INS1,HHEX,HNF1A,HNF4G,HNF1B,MAFA,FOXA2,PKLR,IAPP,PDX1
    Insulin resistance PRKAG2A,PPP2R4,PRKAB1B,OGT,G6PCA.1,OGT.1,PRKCBA,PPARA,PDPK1,PRKCBB
    Type II diabetes mellitus CACNA1G,HK2,PIK3R1,PIK3R2,IRS4,PKLR,PRKCZ,HK3,MAPK1,IKBKB
    Insulin secretion ATP1A4,VAMP2,ATP1A3,ATP1A1,PLCB1,CREB3L1,CREB3L3,GNAQ,ATP1B4,GPR119

    Protein Function

    SLC2A2 has several biochemical functions, for example, D-glucose transmembrane transporter activity,dehydroascorbic acid transporter activity,glucose transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC2A2 itself. We selected most functions SLC2A2 had, and list some proteins which have the same functions with SLC2A2. You can find most of the proteins on our site.

    Function Related Protein
    dehydroascorbic acid transporter activity SLC23A1,SLC2A1
    glucose transmembrane transporter activity SLC2A4,SLC2A3A,SLC2A6,PPBP,SLC2A11B,SLC2A15A,SLC2A5,SLC2A15B,SLC2A1,SLC2A8
    D-glucose transmembrane transporter activity SLC2A13B,SLC2A4,SLC2A1
    insulin receptor binding FRS2A,DOK3,PTPN1,FRS2B,FRS3,SNX4,DOK1,INS,IRS4,PIK3R1

    Interacting Protein

    SLC2A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC2A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC2A2.

    Resources

    Research Area

    Pancreatic Endoderm Cell Markers
    Endodermal Lineage Markers

    References

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