SLC25A1
-
Official Full Name
solute carrier family 25 (mitochondrial carrier -
Overview
This gene encodes a member of the mitochondrial carrier subfamily of solute carrier proteins. Members of this family include nuclear-encoded transporters that translocate small metabolites across the mitochondrial membrane. This protein regulates the movement of citrate across the inner membranes of the mitochondria. Mutations in this gene have been associated with combined D-2- and L-2-hydroxyglutaric aciduria. Pseudogenes of this gene have been identified on chromosomes 7, 11, 16, and 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] -
Synonyms
SLC25A1;solute carrier family 25 (mitochondrial carrier;citrate transporter), member 1;CTP;SEA;D2L2AD;SLC20A3;tricarboxylate transport protein, mitochondrial;citrate transport protein;tricarboxylate carrier protein;solute carrier family 20 (mitochondrial citrate transporter), member 3
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- Bovine
- E.coli
- Mammalian Cell
- HEK293
- E.coli expression system
- His
- Non
- GST
- His&Fc&Avi
Involved Pathway
SLC25A1 involved in several pathways and played different roles in them. We selected most pathways SLC25A1 participated on our site, such as Fatty Acyl-CoA Biosynthesis,Fatty acid, triacylglycerol, and ketone body metabolism,Gluconeogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC25A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Triglyceride Biosynthesis | ACOT13,ACSF3,ACOT11A,ACOT9.2,Agmo,THEM5,ELOVL1A,ACOT11B,DGAT1B,ACOT6 |
| Glucose metabolism | GYG1B,GYG1,SLC25A11,AGL,NHLRC1,SLC25A10,GYG1A,GYG2,SLC25A12,SLC25A1A |
| Metabolism of carbohydrates | FMODA,NHLRC1,GYG1A,B3GNT1,OXSR1,SLC5A4,DSEL,CHST9,SLC25A11,CHP |
| Metabolism of lipids and lipoproteins | COL4A3BP,MED23,SCP2B,GLIPR1,TIAM2,ACSF2,GDF1,SUMF2,PLD6,PPM1LA |
| Metabolism | ZDHHC21,CYB5R3,B3GNT3,ACY3.1,CDS1,ATP5H,CYP2A7,ACY3.2,ITPKB,DDAH2 |
| Fatty acid, triacylglycerol, and ketone body metabolism | CDK19,MED31,MED8,AGPAT6,MED10,ACOT7,Agmo,CTGF,ANKRD1,ACOT2 |
| Gluconeogenesis | SLC25A1A,SLC25A12,SLC25A11,SLC25A10,SLC25A13,GPR19 |
| Fatty Acyl-CoA Biosynthesis | ACOT11,ACOT2,ACOT12,ACOT7,ACSF3,SLC25A1A,ELOVL1A,ACOT9.1,ACOT11B,ACOT13 |
Protein Function
SLC25A1 has several biochemical functions, for example, citrate transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC25A1 itself. We selected most functions SLC25A1 had, and list some proteins which have the same functions with SLC25A1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| citrate transmembrane transporter activity | SLC13A5A,SFXN5,SLC13A5,SLC13A3 |
Interacting Protein
SLC25A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC25A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC25A1.
P;TNFRSF1B;HLA-B;CASP4;YBX1;MAGED1;pepN;CBX4;MYC;FN1;ERBB2;Itgb1;ARAF;MLH1;LIMK2;Tubg1;ILK
Resources
Related Services
Related Products
References
