SLC22A5
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Official Full Name
solute carrier family 22 (organic cation/carnitine transporter), member 5 -
Synonyms
CT1;OCTN2;UST2r
Recombinant Proteins
- Human
- Chicken
- Rat
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&GST
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SLC22A5-3707H | Recombinant Human SLC22A5 protein, His-tagged | E.coli | Human | His | 1-142 aa | |
| SLC22A5-3488C | Recombinant Chicken SLC22A5 | Mammalian Cell | Chicken | His |
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| SLC22A5-5459R | Recombinant Rat SLC22A5 Protein | Mammalian Cell | Rat | His |
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| SLC22A5-1794HCL | Recombinant Human SLC22A5 293 Cell Lysate | HEK293 | Human | Non |
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| Slc22a5-2063M | Recombinant Mouse Slc22a5 Protein, His&GST-tagged | E.coli | Mouse | His&GST | Met1-Pro278 |
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| SLC22A5-5118R | Recombinant Rat SLC22A5 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| SLC22A5-5118R-B | Recombinant Rat SLC22A5 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| SLC22A5-668H | Recombinant Human SLC22A5 Protein, GST-tagged | Wheat Germ | Human | GST | 1-557 aa |
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| SLC22A5-6814HF | Recombinant Full Length Human SLC22A5 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 557 amino acids |
|
Involved Pathway
SLC22A5 involved in several pathways and played different roles in them. We selected most pathways SLC22A5 participated on our site, such as Choline metabolism in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC22A5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Choline metabolism in cancer | WASF2,PDGFD,RHEB,RAC3,PLD1,MAPK8,PIK3R2,PLD2,PRKCA,PDGFC |
Protein Function
SLC22A5 has several biochemical functions, for example, ATP binding,PDZ domain binding,carnitine transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC22A5 itself. We selected most functions SLC22A5 had, and list some proteins which have the same functions with SLC22A5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | PIK3CD,DHX34,DNAH14,DNAH11,SMC4,FLAD1,MAP4K6,KIF5B,EPHB4B,LCK |
| drug transmembrane transporter activity | SLC18A3A,ABCG3,SLC47A2,ABCG2D,SLCO1B2,SLC17A3,SLC22A18,SLC47A1,Abcb1b,ABCG2A |
| symporter activity | SLC24A5,SLC23A1,SLC5A12,SLC6A11A,SLC38A2,SLC38A3,SLC6A4B,SLC25A3,SLC16A8,SLC34A2 |
| quaternary ammonium group transmembrane transporter activity | SLC22A3,SLC22A1,SLC22A2 |
| protein binding | SLC7A11,CHMP4A,ABCD2,ULK2,GPR143,PTPN7,NOX1,TCF3,RARB,DPH1 |
| PDZ domain binding | FZD2,ATP2B3A,GRASP,SSTR2,DLG4,PSEN1,KCNJ4,SNTB1,PLEKHA1,FZD1 |
| carnitine transmembrane transporter activity | SLC22A16 |
Interacting Protein
SLC22A5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC22A5 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC22A5.
Slc22a5
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References
- Bexten, M; Oswald, S; et al. Expression of Drug Transporters and Drug Metabolizing Enzymes in the Bladder Urothelium in Man and Affinity of the Bladder Spasmolytic Trospium Chloride to Transporters Likely Involved in Its Pharmacokinetics. MOLECULAR PHARMACEUTICS 12:171-178(2015).
- Ochiai, H; Kanemaki, N; et al. Distribution, Molecular Structure and Functional Analysis of Carnitine Transporter (SLC22A5) in Canine Lens Epithelial Cells. EXPERIMENTAL ANIMALS 63:467-473(2014).
