SLC22A4
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Official Full Name
solute carrier family 22 (organic cation/ergothioneine transporter), member 4 -
Overview
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is an organic cation transporter and plasma integral membrane protein containing eleven putative transmembrane domains as well as a nucleotide-binding site motif. Transport by this protein is at least partially ATP-dependent. -
Synonyms
SLC22A4;solute carrier family 22 (organic cation/ergothioneine transporter), member 4;solute carrier family 22 member 4;MGC34546;OCTN1;LSTP Like 2;MGC40524;Ergothioneine transporter;ET transporter;Organic cation transporter 1;Organic cation/carnitine transporter 1;RP23-354D12.1;S22A4_HUMAN;Solute carrier family (organic cation transporter), member 4;integral membrane transport protein
Recombinant Proteins
- Zebrafish
- Human
- Chicken
- Rat
- Mammalian Cell
- E.coli
- Insect Cell
- HEK293
- His
- His&T7
- His&Flag&MBP
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SLC22A4-11101Z | Recombinant Zebrafish SLC22A4 | Mammalian Cell | Zebrafish | His |
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| SLC22A4-1212H | Recombinant Human SLC22A4 protein, His & T7-tagged | E.coli | Human | His&T7 | Leu42~Lys141 |
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| SLC22A4-3926C | Recombinant Chicken SLC22A4 | Mammalian Cell | Chicken | His |
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| SLC22A4-5458R | Recombinant Rat SLC22A4 Protein | Mammalian Cell | Rat | His |
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| SLC22A4-1216H | Recombinant Human SLC22A4 Protein (R2-F551), 8×His-MBP, Flag tagged | Insect Cell | Human | His&Flag&MBP | R2-F551 |
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| SLC22A4-5117R | Recombinant Rat SLC22A4 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| SLC22A4-5117R-B | Recombinant Rat SLC22A4 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
SLC22A4 involved in several pathways and played different roles in them. We selected most pathways SLC22A4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC22A4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
SLC22A4 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SLC22A4 itself. We selected most functions SLC22A4 had, and list some proteins which have the same functions with SLC22A4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
SLC22A4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC22A4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC22A4.
Resources
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References
- Beckmann, J; Schubert, J; et al. Expression of choline and acetylcholine transporters in synovial tissue and cartilage of patients with rheumatoid arthritis and osteoarthritis. CELL AND TISSUE RESEARCH 359:465-477(2015).
- Ren, TL; Han, ZJ; et al. Association of SLC22A4 Gene Polymorphism with Rheumatoid Arthritis in the Chinese Population. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY 28:206-210(2014).
