SKA1
-
Official Full Name
spindle and kinetochore associated complex subunit 1 -
Synonyms
SKA1;spindle and kinetochore associated complex subunit 1;C18orf24, chromosome 18 open reading frame 24;spindle and kinetochore-associated protein 1;MGC10200;C18orf24;SKA1_HUMAN;Spindle and kinetochore associated protein 1;Spindle and KT (kinetochore) associated 1;Spindle and KT associated 1
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- Zebrafish
- Mammalian Cell
- E.coli
- HEK293
- HEK293T
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
SKA1 involved in several pathways and played different roles in them. We selected most pathways SKA1 participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,M Phase, which may be useful for your reference. Also, other proteins which involved in the same pathway with SKA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mitotic Metaphase and Anaphase | WAPAL,VRK2,SGOL2,CENPK,NDEL1A,TMPO,KNTC1,MLF1IP,CENPL,RANGAP1B |
| M Phase | CCDC99,CENPN,NCAPD3,DSN1,MASTL,BLZF1,LEMD3,SMC2,CTDNEP1,KNTC1 |
| Mitotic Prometaphase | NDEL1,SKA2,SGOL1,NCAPD2,CLIP1,KNTC1,SPC25,MIS12,SMC4,INCENP |
| RHO GTPase Effectors | WIPF3,NDEL1A,MKL1B,ABI1,RHOGA,DIAPH1,ZWINT,RHOC,NOXA1,RHPN2 |
| Cell cycle | CENPL,NCAPG,TERF1,SMAD2,GADD45A,NUMA1,RBX1,FGFR1OP,ANAPC1,CCNA1 |
| Cell Cycle, Mitotic | PHF8,SET,H3F3D,ZW10,USO1,KNTC1,KIF18A,POLD3,CDKN2D,LIN37 |
| RHO GTPases Activate Formins | CCDC99,NUF2,SGOL2,CLIP1,DSN1,ZWINT,FMNL2,RCC2,MKL1,NSL1 |
| Mitotic Anaphase | NUDC,CENPO,NUF2,CDCA8,AHCTF1,RANGAP1B,ITGB3BP,CENPN,PDS5A,INCENP |
Protein Function
SKA1 has several biochemical functions, for example, microtubule binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SKA1 itself. We selected most functions SKA1 had, and list some proteins which have the same functions with SKA1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| microtubule binding | MARK4,AKAP1,PSRC1,KIF3A,GAS2L2,NUSAP1,MAPRE3,APC2,MAPRE1B,CRYAB |
| protein binding | CHST13,CXADR,TRIM59,PEX3,TRIM44,CTH,PSMD2,COBL,TBRG4,SSH1 |
Interacting Protein
SKA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SKA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SKA1.
SKA2;BLOC1S6;SKA3
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