SIT1
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Official Full Name
signaling threshold regulating transmembrane adaptor 1 -
Overview
Signaling threshold-regulating transmembrane adapter 1 is a protein that in humans is encoded by the SIT1 gene. -
Synonyms
SIT1;signaling threshold regulating transmembrane adaptor 1;suppression inducing transmembrane adaptor 1;signaling threshold-regulating transmembrane adapter 1;SHP2 interacting transmembrane adaptor;SIT;gp30/40;suppression-inducing transmembrane ad
Recombinant Proteins
- Human
- Rat
- Rhesus macaque
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293F
- HEK293T
- Mammalian cells
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
SIT1 involved in several pathways and played different roles in them. We selected most pathways SIT1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SIT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SIT1 has several biochemical functions, for example, SH2 domain binding,kinase binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SIT1 itself. We selected most functions SIT1 had, and list some proteins which have the same functions with SIT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CCDC110,FLNA,GMNN,NLRP3,KRT14,PUM1,RNF144B,COPS7A,BACH1,CXCR7 |
| SH2 domain binding | JAK2,SYP,LCK,LILRB1,GNB2L1,DAG1,NUP62,SRC,SH3PXD2B,IRS1 |
| kinase binding | BCL10,MOB4,SP100,ABI2,STX1A,STUB1,PPP2R5A,PARK2,BTG1,PER1 |
Interacting Protein
SIT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SIT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SIT1.
PTPN11
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