SGK2
-
Official Full Name
serum/glucocorticoid regulated kinase 2 -
Overview
Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, glucocorticoid, follicle stimulating hormone, osmotic shock, and mineralocort -
Synonyms
SGK2;serum/glucocorticoid regulated kinase 2;serine/threonine-protein kinase Sgk2;H-SGK2;dJ138B7.2
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Sf9 Insect Cell
- Mammalian Cell
- HEK293
- Insect Cell
- HEK293T
- Insect (sf21)
- GST
- His&T7
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
SGK2 involved in several pathways and played different roles in them. We selected most pathways SGK2 participated on our site, such as FoxO signaling pathway,Insulin Signaling,Ion channel transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SGK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Transmembrane transport of small molecules | SLC6A20,SLC36A2,SLC2A13B,AQP10B,AQP9B,ANO5,SLC28A2,AQP10,SLC39A14,SLC9A6A |
PI3K-Akt signaling pathway | EFNA2,LOC608458,EFNA3,LAMC3,CSH,COMP,PIK3AP1,CSF1,CSH1,CSH2 |
Insulin Signaling | STXBP2,MAP3K2,GSK3AB,CAP1,STXBP3,FLOT1,INPP4AA,MYO1C,MAP4K5,GRB10 |
FoxO signaling pathway | IKBKB,MAPK1,SOD2,PLK2,MAP2K2B,SMAD4,MAPK3,SETD7,PTENB,MAPK11 |
Ion channel transport | CLCNK,TRPV3,ANO5B,TSC22D3,ATP1A1A.5,CCC2,BSND,ATP1A1A.4,WNK1,CLCN5 |
Stimuli-sensing channels | OSTM1,TRDN,ANO10A,TRPM4A,CLCA1,FKBP1B,TRPC4A,WNK2,BEST3,TPCN1 |
Protein Function
SGK2 has several biochemical functions, for example, ATP binding,calcium channel regulator activity,chloride channel regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SGK2 itself. We selected most functions SGK2 had, and list some proteins which have the same functions with SGK2. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
chloride channel regulator activity | BSND,SGK1,SGK2A,SLC9A3R1,SGK3,CHRNA7,SGK2B |
potassium channel regulator activity | PRKCZ,NEDD4L,KCNIP1,SGK2B,SGK2A,KCNS3,CHP,YWHAE,ANK2,KCNMB2 |
sodium channel regulator activity | GPLD1,FXYD3,NEDD4L,FGF12,RANGRF,FXYD6,GPD1L,AGT,PRSS30,SCN3B |
protein serine/threonine kinase activity | PRKCB,STK32A,STK16,RPS6KA1,MAP4K1,PHKG1B,KSR2,DYRK1A,CDK14,GAK |
calcium channel regulator activity | GRM3,GNB2,CAV3,GRM6A,NRXN3,PRKG1,STIM2,CACNA2D1,CRISP1,HPCAL4 |
ATP binding | JAK2,UBE2Z,HSPA9,PLK2B,TEC,UBE2I,ERN2,NADKD1,IP6K1,ATP2A1 |
Interacting Protein
SGK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SGK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SGK2.
HSP90AB1;IL3RA;DDX5;TCP1;CCT6A;CCT5;CCT3;CCT8;CCT4;ILF3;FKBP5;CCT7
Resources
Related Services
Related Products
References