SGK2

  • Official Full Name

    serum/glucocorticoid regulated kinase 2
  • Overview

    Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, glucocorticoid, follicle stimulating hormone, osmotic shock, and mineralocort
  • Synonyms

    SGK2;serum/glucocorticoid regulated kinase 2;serine/threonine-protein kinase Sgk2;H-SGK2;dJ138B7.2

Recombinant Proteins

  • Human
  • Rat
  • Mouse
  • E.coli
  • Sf9 Insect Cell
  • Mammalian Cell
  • HEK293
  • Insect Cell
  • HEK293T
  • Insect (sf21)
  • GST
  • His&T7
  • His
  • Non
  • Myc&DDK
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
SGK2-2631H Recombinant Human SGK2, GST-tagged E.coli Human GST C-term-397aa
SGK2-1842H Recombinant Human SGK2 protein, His & T7-tagged E.coli Human His&T7 Val40~Pro311
SGK2-429H Recombinant Human SGK2, GST-tagged, Active Sf9 Insect Cell Human GST
SGK2-5365R Recombinant Rat SGK2 Protein Mammalian Cell Rat His
SGK2-659H Recombinant Human Serum/Glucocorticoid Regulated Kinase 2 E.coli Human Non
SGK2-1885HCL Recombinant Human SGK2 293 Cell Lysate HEK293 Human Non
SGK2-1182H Recombinant Human SGK2 Protein (Q2-C427), Tag Free Insect Cell Human Non Q2-C427
SGK2-1183H Recombinant Human SGK2 Protein (Q2-C427), GST tagged Insect Cell Human GST Q2-C427
SGK2-2612H Recombinant Human SGK2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
SGK2-3784HF Active Recombinant Full Length Human SGK2 Protein, GST-tagged Insect (sf21) Human GST Full L. 1-367
SGK2-5024R Recombinant Rat SGK2 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
SGK2-5024R-B Recombinant Rat SGK2 Protein Pre-coupled Magnetic Beads HEK293 Rat
SGK2-5515H Recombinant Human SGK2 Protein (Thr40-Leu311), N-His tagged E.coli Human His Thr40-Leu311
Sgk2-5825M Recombinant Mouse Sgk2 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK

    Involved Pathway

    SGK2 involved in several pathways and played different roles in them. We selected most pathways SGK2 participated on our site, such as FoxO signaling pathway,Insulin Signaling,Ion channel transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SGK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Transmembrane transport of small molecules SLC6A20,SLC36A2,SLC2A13B,AQP10B,AQP9B,ANO5,SLC28A2,AQP10,SLC39A14,SLC9A6A
    PI3K-Akt signaling pathway EFNA2,LOC608458,EFNA3,LAMC3,CSH,COMP,PIK3AP1,CSF1,CSH1,CSH2
    Insulin Signaling STXBP2,MAP3K2,GSK3AB,CAP1,STXBP3,FLOT1,INPP4AA,MYO1C,MAP4K5,GRB10
    FoxO signaling pathway IKBKB,MAPK1,SOD2,PLK2,MAP2K2B,SMAD4,MAPK3,SETD7,PTENB,MAPK11
    Ion channel transport CLCNK,TRPV3,ANO5B,TSC22D3,ATP1A1A.5,CCC2,BSND,ATP1A1A.4,WNK1,CLCN5
    Stimuli-sensing channels OSTM1,TRDN,ANO10A,TRPM4A,CLCA1,FKBP1B,TRPC4A,WNK2,BEST3,TPCN1

    Protein Function

    SGK2 has several biochemical functions, for example, ATP binding,calcium channel regulator activity,chloride channel regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SGK2 itself. We selected most functions SGK2 had, and list some proteins which have the same functions with SGK2. You can find most of the proteins on our site.

    Function Related Protein
    chloride channel regulator activity BSND,SGK1,SGK2A,SLC9A3R1,SGK3,CHRNA7,SGK2B
    potassium channel regulator activity PRKCZ,NEDD4L,KCNIP1,SGK2B,SGK2A,KCNS3,CHP,YWHAE,ANK2,KCNMB2
    sodium channel regulator activity GPLD1,FXYD3,NEDD4L,FGF12,RANGRF,FXYD6,GPD1L,AGT,PRSS30,SCN3B
    protein serine/threonine kinase activity PRKCB,STK32A,STK16,RPS6KA1,MAP4K1,PHKG1B,KSR2,DYRK1A,CDK14,GAK
    calcium channel regulator activity GRM3,GNB2,CAV3,GRM6A,NRXN3,PRKG1,STIM2,CACNA2D1,CRISP1,HPCAL4
    ATP binding JAK2,UBE2Z,HSPA9,PLK2B,TEC,UBE2I,ERN2,NADKD1,IP6K1,ATP2A1

    Interacting Protein

    SGK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SGK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SGK2.

    HSP90AB1;IL3RA;DDX5;TCP1;CCT6A;CCT5;CCT3;CCT8;CCT4;ILF3;FKBP5;CCT7

    Resources

    References

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