SESN2

  • Official Full Name

    sestrin 2

  • Overview

    This gene encodes a member of the sestrin family of PA26-related proteins. The encoded protein may function in the regulation of cell growth and survival. This protein may be involved in cellular response to different stress conditions.

  • Synonyms

    SESN2;sestrin 2;sestrin-2;DKFZp761M0212;HI95;SES2;SEST2;hypoxia induced gene 95;DKFZp761M02121

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Zebrafish
  • Mouse
  • E.coli
  • Mammalian Cell
  • HEK293
  • Mammalian cells
  • HEK293T
  • GST
  • His
  • His&T7
  • Non
  • Flag
  • His&Fc&Avi
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
SESN2-2605H Recombinant Human SESN2, GST-tagged E.coli Human GST 1-117aa
SESN2-2606H Recombinant Human SESN2, GST-tagged E.coli Human GST C-term-350aa
SESN2-4160R Recombinant Rhesus monkey SESN2 Protein, His-tagged Mammalian Cell Rhesus macaque His
SESN2-4932Z Recombinant Zebrafish SESN2 Mammalian Cell Zebrafish His
Sesn2-8101M Recombinant Mouse Sesn2 protein, His & T7-tagged E.coli Mouse His&T7 Ser41~Thr480
SESN2-1930HCL Recombinant Human SESN2 293 Cell Lysate HEK293 Human Non
SESN2-1376HFL Recombinant Full Length Human SESN2 Protein, C-Flag-tagged Mammalian cells Human Flag Full L.
SESN2-1984H Recombinant Human SESN2 Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
SESN2-1984H-B Recombinant Human SESN2 Protein Pre-coupled Magnetic Beads HEK293 Human
SESN2-3977R Recombinant Rhesus Macaque SESN2 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
SESN2-3977R-B Recombinant Rhesus Macaque SESN2 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
Sesn2-5795M Recombinant Mouse Sesn2 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
SESN2-6245H Recombinant Human SESN2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK

    Involved Pathway

    SESN2 involved in several pathways and played different roles in them. We selected most pathways SESN2 participated on our site, such as p signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SESN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    p signaling pathway CD82A,IGF1,Casp3,CYCSB,PTENA,STEAP3,TP53,BBC3,TRP53,THBS1

    Protein Function

    SESN2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SESN2 itself. We selected most functions SESN2 had, and list some proteins which have the same functions with SESN2. You can find most of the proteins on our site.

    Function Related Protein
    protein binding USP47,LARS,RND3,LRRC20,KLRG1,GSDMD,MAP2K6,SMARCAD1,ABLIM1,C10orf46

    Interacting Protein

    SESN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SESN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SESN2.

    SQSTM1;Ulk1;Sqstm1;MDM2;ATG13;ULK1;RB1CC1

    Resources

    References

    • Brazina, J; Svadlenka, J; et al. DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase. CELL CYCLE 14:375-387(2015).
    • Yang, JH; Kim, KM; et al. Role of sestrin2 in the regulation of proinflammatory signaling in macrophages. FREE RADICAL BIOLOGY AND MEDICINE 78:156-167(2015).

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